Termination of transcription is important for establishing gene punctuation marks. It is also
critical for suppressing many of the pervasive transcription events occurring throughout …

Processing and maturation of precursor RNA species is coupled to RNA polymerase II
transcription. Co‐transcriptional RNA processing helps to ensure efficient and proper …

Abstract The Nuclear Exosome Targeting (NEXT) complex is a key cofactor of the
mammalian nuclear exosome in the removal of Promoter Upstream Transcripts (PROMPTs) …

Termination of RNA polymerase II (Pol II) transcription is an important step in the
transcription cycle, which involves the dislodgement of polymerase from DNA, leading to …

The RNA polymerase II transcription cycle is often divided into three major stages: initiation,
elongation, and termination. Research over the last decade has blurred these divisions and …

Pervasive transcription is a widespread phenomenon leading to the production of a plethora
of non‐coding RNA s (nc RNA s) without apparent function. Pervasive transcription poses a …

In Saccharomyces cerevisiae, transcription termination at protein-coding genes is coupled to
the cleavage of the nascent transcript, whereas most non-coding RNA transcription relies on …

Pervasive transcription generates many unstable non-coding transcripts in budding yeast.
The transcription of such noncoding RNAs, in particular antisense RNAs (asRNAs), has …

RNA polymerase (RNAP) II frequently transcribes non-protein-coding DNA sequences in
eukaryotic genomes into long noncoding RNA (lncRNA). Distinct molecular mechanisms …

Abstract The superfamily 1B (SF 1B) helicase Sen1 is an essential protein that plays a key
role in the termination of non‐coding transcription in yeast. Here, we identified the~ 90 kDa …