Multiple regulatory mechanisms work to ensure that eukaryotic transcription maintains
mRNA pools and subsequent protein synthesis. When errors in transcription occur …

Hydrogen-deuterium exchange coupled to mass spectrometry (HDX-MS) is a powerful
analytical method for monitoring the dynamics of protein systems in solution. HDX-MS …

Eukaryotic genomes are subjected to pervasive transcription. However, these pervasive
transcripts such as Cryptic Unstable Transcripts (CUTs) are rapidly degraded by the nuclear …

Cwf15 (Complexed with cdc5 protein 15) es un factor de procesamiento de RNA, esencial y
evolutivamente conservado de levadura a humano, que se ha demostrado que interactúa …

Transcription is the process whereby RNA molecules are synthetized using DNA as the
template. In eukaryotic cells, this process is carried out by three different kinds of RNA …

The RNA exosome is an evolutionary conserved 3 to 5 exoribonuclease multi-subunit
complex involved in the processing and/or degradation of almost every class of RNA to …

Archive ouverte UNIGE Mechanisms and Persistence of Chromatin-Mediated Antisense
Transcription Interference Page 1 Archive ouverte UNIGE https://archive-ouverte.unige.ch …

One of the most fascinating discoveries over the last years on the field of gene expression
has been the finding that transcription is not restricted to annotated genes but actually …

In Saccharomyces cerevisiae, the nuclear exosome/Rrp6p/TRAMP participates in the 3'-end
processing of several precursor non-coding RNAs. Here we demonstrate that the depletion …

Pervasive transcription is a widespread phenomenon leading to the production of a plethora
of non-coding RNAs (ncRNAs) without apparent function. Pervasive transcription poses a …