Inorganic nanomaterials have gained increasing attention in radiation oncology, owing to
their radiation therapy enhancing properties. To accelerate candidate material selection and …

Genomics has greatly increased the understanding of the study of breast cancer (BC) and
has shaped the concept of intra-tumor heterogeneity, currently recognized as a propelling …

V937 is an investigational, genetically unmodified Kuykendall strain of coxsackievirus A21,
which has been evaluated in the clinic for advanced solid tumor malignancies. V937 …

Breast cancer remains a leading lethal cancer in women globally, with the HER2+ positive
subtype associated with a higher chance of therapeutic resistance. Treatments tailored …

Organoids and organs-on-a-chip are currently the two major families of 3D advanced
organotypic in vitro culture systems, aimed at reconstituting miniaturized models of …

In recent years, scientific understanding of the changes radiation makes to the various
tissues of the body has vastly increased. Identification of biological markers of radiation …

Organotypic three-dimensional (3D) cell cultures more accurately mimic the characteristics
of solid tumors in vivo in comparison with traditional two-dimensional (2D) monolayer cell …

Microtissues, sometimes referred to as organoids or tumour-spheroids, are increasingly
common cell culture tools. They can be used as tissue models for drug testing or as building …

Résumé Au Canada, le cancer de la prostate (CaP) est le type de cancer le plus courant
chez les hommes. Environ 30% des patients atteints de CaP développent une récidive …

Pancreatic ductal adenocarcinoma (PDAC) is a high-mortality cancer with no effective
treatment options for the majority of patients. Notably, tumour cell behaviour and response to …