Pleural mesothelioma (PMe): The evolving molecular knowledge of a rare and aggressive cancer
M Rigon, L Mutti, M Campanella - Molecular Oncology, 2024 - Wiley Online Library
Mesothelioma is a type of late‐onset cancer that develops in cells covering the outer surface
of organs. Although it can affect the peritoneum, heart, or testicles, it mainly targets the lining …
of organs. Although it can affect the peritoneum, heart, or testicles, it mainly targets the lining …
Immune checkpoint inhibitors as first line in advanced melanoma: Evaluating progression‐free survival based on reconstructed individual patient data
Background In patients with advanced melanoma, immune‐checkpoint inhibitors (ICIs)
represent the mainstay for first line treatment. Recently, relatlimab+ nivolumab was …
represent the mainstay for first line treatment. Recently, relatlimab+ nivolumab was …
The STING agonist, DMXAA, reduces tumor vessels and enhances mesothelioma tumor antigen presentation yet blunts cytotoxic T cell function in a murine model
PT Graham, AK Nowak, SMJ Cornwall, I Larma… - Frontiers in …, 2022 - frontiersin.org
We assessed the murine Stimulator of Interferon Genes (STING) agonist, DMXAA, for anti-
mesothelioma potential using the AE17-sOVA model that expresses ovalbumin (OVA) as a …
mesothelioma potential using the AE17-sOVA model that expresses ovalbumin (OVA) as a …
ATG5 as biomarker for early detection of malignant mesothelioma
M Tomasetti, F Monaco, O Strogovets, L Volpini… - BMC Research …, 2023 - Springer
Objectives Malignant pleural mesothelioma (MPM) is an aggressive disease with grim
prognosis due to lack of effective treatment options. Disease prediction in association with …
prognosis due to lack of effective treatment options. Disease prediction in association with …
Immune checkpoint inhibitors in malignant pleural mesothelioma: a systematic review and meta-analysis
Simple Summary Many clinical trials have investigated the role of Immune Checkpoint
Inhibitors (ICIs) in pleural mesothelioma (PM), with contrasting results. We performed a …
Inhibitors (ICIs) in pleural mesothelioma (PM), with contrasting results. We performed a …
Analysis of new treatments proposed for malignant pleural mesothelioma raises concerns about the conduction of clinical trials in oncology
In this commentary, using existing clinical trial data and FDA approvals we propose that
there is currently a critical need for an appropriate balancing between the financial impact of …
there is currently a critical need for an appropriate balancing between the financial impact of …
Intratumor microbiota as a novel potential prognostic indicator in mesothelioma
F Pentimalli, M Krstic-Demonacos, C Costa… - Frontiers in …, 2023 - frontiersin.org
Introduction Despite increased attention on immunotherapy, primarily immune checkpoint
blockade, as a therapeutic approach for mesothelioma (MMe), its efficacy and tolerability …
blockade, as a therapeutic approach for mesothelioma (MMe), its efficacy and tolerability …
Define the two molecular subtypes of epithelioid malignant pleural mesothelioma
Malignant pleural mesothelioma (MPM) is a fatal disease of respiratory system. Despite the
availability of invasive biomarkers with promising results, there are still significant diagnostic …
availability of invasive biomarkers with promising results, there are still significant diagnostic …
Mesothelioma mouse models with mixed genomic states of chromosome and microsatellite instability
Y Song, SS Baxter, L Dai, C Sanders, S Burkett… - Cancers, 2022 - mdpi.com
Simple Summary Only a limited number of murine mesothelioma cell lines have been
developed to date. We sought to expand this number and to characterize the models in …
developed to date. We sought to expand this number and to characterize the models in …
[HTML][HTML] The “One-to-Many” Survival Analysis to Evaluate a New Treatment in Comparison With Therapeutic Alternatives Based on Reconstructed Patient Data …
A Messori, M Rivano, L Cancanelli, V Damuzzo… - Cureus, 2022 - ncbi.nlm.nih.gov
Objective This paper presents a preliminary experience based on the" one-to-many"
approach of the Shiny method. Numerous (or" many") treatments for advanced or metastatic …
approach of the Shiny method. Numerous (or" many") treatments for advanced or metastatic …