Novel approaches to combat medical device-associated biofilms

X Li, L Sun, P Zhang, Y Wang - Coatings, 2021 - mdpi.com
Biofilms are aggregates formed as a protective survival state by microorganisms to adapt to
the environment and can be resistant to antimicrobial agents and host immune responses …

Treatment options in PJI–is two-stage still gold standard?

I Lazic, C Scheele, F Pohlig… - Journal of …, 2021 - Elsevier
Total knee arthroplasty (TKA) is a successful treatment for osteoarthritis with good clinical
outcomes 1, 2. Periprosthetic joint infection (PJI) in TKA has a low incidence between 0.5 …

[HTML][HTML] Successful two-stage exchange arthroplasty for periprosthetic infection following total knee arthroplasty: the impact of timing on eradication of infection

I Vielgut, G Schwantzer, A Leithner… - … Journal of Medical …, 2021 - ncbi.nlm.nih.gov
Background: Periprosthetic joint infection (PJI) represents a serious complication following
total knee arthroplasty. In the setting of chronic infections, the two-staged approach has …

[HTML][HTML] Improved osteogenic activity and inhibited bacterial biofilm formation on andrographolide-loaded titania nanotubes

E Feng, K Shen, F Lin, W Lin, T Zhang… - Annals of …, 2020 - ncbi.nlm.nih.gov
Background Delivery of local drugs with a titania nanotube is an attractive approach to
combat implant-related infection. Our earlier study has confirmed that nanotubes loaded with …

A comparative study on hemostasis effect of different application methods and time of tranexamic acid in total hip arthroplasty

W Zhou, H Lv, H Zhang, Y Ding, J Zhou, H Tong… - European Journal of …, 2024 - Springer
Objectives To analyze the hemostatic effect of different application methods and time of
tranexamic acid (TXA) on primary unilateral total hip arthroplasty. Methods A total of 126 …

Cost drivers in two-stage treatment of hip periprosthetic joint infection with an antibiotic coated cement hip spacer

LT Charalambous, CM Wixted, BI Kim… - The Journal of …, 2023 - Elsevier
Background The current gold standard for treating chronic Periprosthetic Joint Infection (PJI)
is a 2-stage revision arthroplasty. There has been little investigation into what specific …

Static spacers play a crucial role in the treatment of complex periprosthetic joint infections of the knee

A Lunz, GW Omlor, MN Voss… - Knee Surgery …, 2024 - Wiley Online Library
Purpose To determine the superior spacer design, a growing number of studies are
comparing treatment results between patients having been treated with articulating and …

Quality of life, infection control, and complication rates using a novel custom-made articulating hip spacer during two-stage revision for periprosthetic joint infection

A Lunz, GW Omlor, G Schmidt, B Moradi… - Archives of Orthopaedic …, 2021 - Springer
Introduction Two-stage revision remains the gold standard treatment for most chronically
infected and complex total hip arthroplasty infections. To improve patient outcome and …

Introducing image-guided synovial aspiration and biopsy in assessing peri-prosthetic joint infection: an early single-centre experience

R Rajakulasingam, L Cleaver, M Khoo, I Pressney… - Skeletal Radiology, 2021 - Springer
Aim Synovial sampling can be used in the diagnosis of peri-prosthetic joint infection (PJI).
The purpose of this study was to establish the role of simultaneous image-guided synovial …

[HTML][HTML] Periprosthetic Joint Infection With Actinomyces radingae May Lead to the Identification of a Neglected Source of Intraoperative Contamination

H Kuttner, S Pfister, TF Moriarty, C Meier, P Wahl - Arthroplasty Today, 2022 - Elsevier
Periprosthetic joint infection remains a major complication in arthroplasty. We present the
first description of a case of periprosthetic joint infection with Actinomyces radingae …