L-5-hydroxytryptophan (5-HTP) is both a drug and a natural component of some dietary
supplements. 5-HTP is produced from tryptophan by tryptophan hydroxylase (TPH), which is …

Fibromyalgia (FM) is characterized by chronic widespread musculoskeletal pain associated
with sleep problems, fatigue, depression, and anxiety. The persistence of pain, impairment …

Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a chronic debilitating
disease characterized by severe and disabling fatigue that fails to improve with rest; it is …

Fibromyalgia is characterized by diffuse musculoskeletal pain, fatigue, poor sleep, and other
somatic symptoms. It can occur in children and adults, and is found worldwide and across …

Fibromyalgia syndrome (FMS) is a pain disorder characterized by chronic widespread pain,
fatigue, and sleep disturbance, in the absence of any well-defined underlying organic …

Background Previous randomized controlled trials (RCTs) suggested that gut microbiota-
based therapies may be effective in treating autoimmune diseases, but a systematic …

Background: Fibromyalgia is a clinical condition that affects 1% to 5% of the population. No
proper therapy has been currently found. It has been described that inflammation plays a …

Fibromyalgia can be defined as a chronic pain condition, affecting the musculoskeletal
system, etiology and pathophysiology of which is sufficiently understudied. Despite the fact …

Objectives: The present study compared physical, psychological, social well-being, and
perceived stigmatization in individuals with clearly defined symptoms and underlying …

In recent years, antioxidant supplements have become popular to counteract the effects of
oxidative stress in fibromyalgia and one of its most distressing symptoms, pain. The aim of …