Risk assessment in patients with pulmonary arterial hypertension in the era of COVID 19 pandemic and the telehealth revolution: state of the art review

MW Milks, S Sahay, RL Benza, HW Farber - The Journal of Heart and Lung …, 2021 - Elsevier
Patients affected by pulmonary arterial hypertension (PAH) benefit from intensive,
continuous clinical monitoring to guide escalation of treatments that carry the potential to …

Clinical pharmacokinetics and pharmacodynamics of the endothelin receptor antagonist macitentan

PN Sidharta, A Treiber, J Dingemanse - Clinical pharmacokinetics, 2015 - Springer
Pulmonary arterial hypertension (PAH) is a progressive disease of the lung vascular system,
which leads to right-sided heart failure and ultimately death if untreated. Treatments to …

Berberine attenuates hypoxia‐induced pulmonary arterial hypertension via bone morphogenetic protein and transforming growth factor‐β signaling

M Chen, H Shen, L Zhu, H Yang, P Ye… - Journal of Cellular …, 2019 - Wiley Online Library
Hypoxia‐induced excessive pulmonary artery smooth muscle cell (PASMC) proliferation
plays an important role in the pathology of pulmonary arterial hypertension (PAH). Berberine …

Comparative effectiveness of pharmacologic interventions for pulmonary arterial hypertension: a systematic review and network meta-analysis

S Jain, R Khera, S Girotra, D Badesch, Z Wang… - Chest, 2017 - Elsevier
Background We conducted a systematic review and network meta-analysis to examine
comparative efficacy and tolerability of pharmacologic interventions for pulmonary arterial …

Use of pulmonary arterial hypertension–approved therapy in the treatment of non–group 1 pulmonary hypertension at US referral centers

AW Trammell, ME Pugh, JH Newman… - Pulmonary …, 2015 - journals.sagepub.com
Pulmonary hypertension (PH) is a frequent complication of left heart disease and
parenchymal lung disease, and it portends increased mortality. A growing number of …

Диагностика и коррекция расстройств системы гемостаза

СВ Синьков, ИБ Заболотских, ЕВ Ройтман - 2017 - elibrary.ru
В книге рассмотрены основные положения физиологии системы гемостаза и
диагностики ее нарушений, дана характеристика фармакологических препаратов …

Riociguat: a soluble guanylate cyclase stimulator for the treatment of pulmonary hypertension

TY Lian, X Jiang, ZC Jing - Drug design, development and therapy, 2017 - Taylor & Francis
Despite advances in treatments and improved survival, patients with pulmonary
hypertension still experience poor exercise and functional capacity, which has a significant …

Pulmonary arterial hypertension in pregnancy

W Ballard, B Dixon, CA McEvoy… - Cardiology …, 2021 - cardiology.theclinics.com
Pulmonary arterial hypertension (PAH) is a rare disease that has significant implications with
regard to morbidity and mortality in those affected. With a prevalence of 15 to 60 cases per …

Riociguat: a novel new drug for treatment of pulmonary hypertension

CT Makowski, RW Rissmiller… - … : The Journal of Human …, 2015 - Wiley Online Library
Riociguat is the first approved medication from the novel class of soluble guanylate cyclase
(sGC) stimulators and the only agent approved for treating both chronic thromboembolic …

A novel approach to perioperative risk assessment for patients with pulmonary hypertension

HJ Hassan, T Housten, A Balasubramanian… - ERJ Open …, 2021 - Eur Respiratory Soc
Rationale Pulmonary hypertension (PH) is associated with significant perioperative
morbidity and mortality. We hypothesised that pulmonary arterial hypertension (PAH) …