Connective tissue disease–associated pulmonary arterial hypertension

YK Sung, L Chung - Rheumatic Disease Clinics, 2015 - rheumatic.theclinics.com
Pulmonary hypertension (PH) is a disease that is strictly defined by having a resting mean
pulmonary artery pressure (mPAP) of 25 mm Hg or greater as measured by right heart …

Bioactive compounds from coptidis rhizoma alleviate pulmonary arterial hypertension by inhibiting pulmonary artery smooth muscle cells' proliferation and migration

S Luo, J Kan, J Zhang, P Ye, D Wang… - Journal of …, 2021 - journals.lww.com
Pulmonary arterial hypertension (PAH) is a devastating disorder characterized by excessive
proliferation and vasoconstriction of small pulmonary artery vascular smooth muscle cells …

[HTML][HTML] Pulmonary arterial hypertension in the setting of scleroderma is different than in the setting of lupus: a review

IS Bazan, KA Mensah, AA Rudkovskaia… - Respiratory …, 2018 - Elsevier
Pulmonary hypertension (PH) is a clinical syndrome that is subdivided into five groups per
the World Health Organization (WHO) classification, based largely on hemodynamic and …

Emerging therapeutics in pulmonary hypertension

MK Hensley, A Levine… - American Journal of …, 2018 - journals.physiology.org
Pulmonary hypertension (PH) is a progressive and often fatal illness presenting with
nonspecific symptoms of dyspnea, lower extremity edema, and exercise intolerance …

Mapping the evolution of inhaled drug delivery research: Trends, collaborations, and emerging frontiers

X Li, Z Su, C Wang, W Wu, Y Zhang, C Wang - Drug Discovery Today, 2023 - Elsevier
Highlights•Bibliometric analysis of data acquired from the Web of Science Core Collection
database were assessed via VOSviewer and CiteSpace.•The current state, emerging trends …

Making the GRADE: CHEST updates its methodology

RL Diekemper, S Patel, SA Mette, J Ornelas… - Chest, 2018 - Elsevier
The American College of Chest Physicians (CHEST) has been at the forefront of evidence-
based clinical practice guideline development for more than 2 decades. In 2006, CHEST …

[HTML][HTML] Current trends in candidate selection, contraindications, and indications for lung transplantation

A Arjuna, MT Olson, R Walia - Journal of thoracic disease, 2021 - ncbi.nlm.nih.gov
Lung transplantation is an established treatment option that can improve quality of life and
prolong survival for select patients diagnosed with end-stage lung disease. Given the gaps …

Evaluation and management approaches for scleroderma lung disease

SR Schoenfeld, FV Castelino - Therapeutic advances in …, 2017 - journals.sagepub.com
Interstitial lung disease (ILD) and pulmonary arterial hypertension (PAH) are leading causes
of morbidity and mortality in systemic sclerosis (SSc). As symptoms are often under-reported …

Comparative assessment of efficacy and safety of ambrisentan and bosentan in patients with pulmonary arterial hypertension: a meta‐analysis

Q Zhao, N Guo, J Chen, D Parks… - Journal of Clinical …, 2022 - Wiley Online Library
What is known and objective Two endothelin receptor antagonists, ambrisentan and
bosentan, have been demonstrated to be effective individually compared with placebo in the …

[HTML][HTML] Healthcare burden of pulmonary hypertension owing to lung disease and/or hypoxia

GA Heresi, DM Platt, W Wang, CH Divers… - BMC pulmonary …, 2017 - Springer
Background Group 3 pulmonary hypertension (PH) encompasses PH owing to lung
diseases and/or hypoxia. Treatment patterns, healthcare resource use, and economic …