The Translational Role of miRNA in Polycystic Ovary Syndrome: From Bench to Bedside—A Systematic Literature Review

SG Vitale, AM Fulghesu, M Mikuš, R Watrowski… - Biomedicines, 2022 - mdpi.com
MicroRNAs (miRNAs) are small, non-coding RNAs that are essential for the regulation of
post-transcriptional gene expression during tissue development and differentiation. They are …

Exosomal miR-143-3p derived from follicular fluid promotes granulosa cell apoptosis by targeting BMPR1A in polycystic ovary syndrome

Y Zhao, S Pan, Y Li, X Wu - Scientific reports, 2022 - nature.com
Polycystic ovary syndrome (PCOS) is an endocrine disorder that occurs in women of
reproductive age. Anovulation caused by abnormal follicular development is still the main …

The emerging roles and therapeutic potential of extracellular vesicles in infertility

G Zhou, Y Gu, F Zhou, M Zhang, G Zhang… - Frontiers in …, 2021 - frontiersin.org
Infertility is becoming much more common and affects more couples. The past years
witnessed the rapid development of the diagnosis and treatment upon infertility, which give …

[HTML][HTML] Characterization of altered microRNAs related to different phenotypes of polycystic ovarian syndrome (PCOS) in serum, follicular fluid, and cumulus cells

HM Rad, SJ Mowla, F Ramazanali… - Taiwanese Journal of …, 2022 - Elsevier
Objective Polycystic ovarian syndrome (PCOS) is a metabolic syndrome in which
steroidogenesis, folliculogenesis, and cellular adhesion play crucial roles in its prognosis …

Oviductal extracellular vesicles enhance porcine in vitro embryo development by modulating the embryonic transcriptome

AS de Alcântara-Neto, C Cuello, R Uzbekov… - Biomolecules, 2022 - mdpi.com
Oviductal extracellular vesicles (oEVs) have been identified as important components of the
oviductal fluid (OF) and have been pointed to as key modulators of gamete/embryo-maternal …

MicroRNAs secreted by human preimplantation embryos and IVF outcome

S Kamijo, T Hamatani, H Sasaki, H Suzuki… - Reproductive Biology …, 2022 - Springer
Objective To generate an effective embryo prediction model and identify a non-invasive
evaluation method by analyzing microRNAs (miRNAs) in embryo culture medium. Design …

Expression of microRNA let-7 in cleavage embryos modulates cell fate determination and formation of mouse blastocysts

W Liu, J Chen, C Yang, KF Lee, YL Lee… - Biology of …, 2022 - academic.oup.com
After fertilization, the zygote undergoes cell division. Up to the 8-cell stage, the blastomeres
of mouse preimplantation embryos are morphologically identical. The first cell differentiation …

MicroRNAs in POI, DOR and POR

J Luo, Z Sun - Archives of Gynecology and Obstetrics, 2023 - Springer
Purpose Premature ovarian insufficiency (POI) is a clinical syndrome defined by loss of
ovarian activity before the age of 40 years. However, the etiology of approximately 90 …

Two single nucleotide variants in the miR‐23a promoter affect granulosa cell apoptosis

S Wang, Y Li, X Du, Q Li - Animal Genetics, 2023 - Wiley Online Library
Abstract microRNAs (miRNAs) are well known to be important in mammalian female fertility.
However, the genetic regulation of miRNAs associated with female fertility remains largely …

Evaluation of Serum MiR-184 and MiR-326 Expression in PCOS Subjects: Correlation with PCOS Related Parameters.

C Gao, L Guo, Z Jiang, L Cao - Clinical Laboratory, 2022 - search.ebscohost.com
Background: MicroRNA (miRNA) is an endogenous non-coding single-stranded RNA with
highly conserved characteristics, which has been proven to regulate gene expression and …