Assessing seizure liability in vitro with voltage-sensitive dye imaging in mouse hippocampal slices
Y Utsumi, M Taketoshi, M Miwa, Y Tominaga… - Frontiers in Cellular …, 2023 - frontiersin.org
Non-clinical toxicology is a major cause of drug candidate attrition during development. In
particular, drug-induced seizures are the most common finding in central nervous system …
particular, drug-induced seizures are the most common finding in central nervous system …
Functional dissection of ipsilateral and contralateral neural activity propagation using voltage-sensitive dye imaging in mouse prefrontal cortex
P Gusain, M Taketoshi, Y Tominaga, T Tominaga - Eneuro, 2023 - eneuro.org
Prefrontal cortex (PFC) intrahemispheric activity and the interhemispheric connection have a
significant impact on neuropsychiatric disorder pathology. This study aimed to generate a …
significant impact on neuropsychiatric disorder pathology. This study aimed to generate a …
[HTML][HTML] Imaging of Evoked Cortical Depolarizations Using Either ASAP2s, or chi-VSFP, or Di-4-Anepps, or Autofluorescence Optical Signals
KD Milicevic, MH Zhu, BL Barbeau, O Baser… - Journal of integrative …, 2023 - imrpress.com
Background: Population voltage imaging is used for studying brain physiology and brain
circuits. Using a genetically encoded voltage indicator (GEVI),“VSFP” or “ASAP2s”, or a …
circuits. Using a genetically encoded voltage indicator (GEVI),“VSFP” or “ASAP2s”, or a …