The ovary, the female gonad, serves as the source for the germ cells as well as the major
supplier of steroid sex hormones. During embryonic development, the primordial germ cells …

The growth of tumour cells as three‐dimensional multicellular spheroids in vitro has led to
important insights in tumour biology, since properties of the in vivo‐tumour such as …

Angiogenesis is the development of blood vessels from an existing vasculature. This
process is fundamental to both physiological wound healing and the growth of malignant …

The ovarian corpus luteum plays a critical role in reproduction because it is the primary
source of circulating progesterone. After ovulation, as the corpus luteum forms from the wall …

A characteristic of solid tumors is their heterogeneous distribution of blood flow, with
significant hypoxia and acidity in low-flow regions. We review effects of heterogeneous …

Etiology of endometrial cancer (EMC) is not fully understood. Animal models with rapidly
and spontaneously developing EMC will help explore mechanisms of cancer initiation and …

Recent research using multicellular tumor spheroids has resulted in new insights in the
regulation of invasion and metastasis, angiogenesis and cell cycle kinetics. The onset and …

Novel products comprising conditioned cell culture medium compositions and methods of
use are described. The con ditioned cell medium compositions of the invention may be …

This study was designed to investigate the effects of inhibition of thecal angiogenesis on
follicular development in the marmoset monkey (Callithrix jacchus). To inhibit vascular …

The ovarian follicle provides the oocyte with the ideal environment for growth and
development in preparation for ovulation and fertilisation. The follicle undergoes many …