Plac8 is an inducer of C/EBPβ required for brown fat differentiation, thermoregulation, and control of body weight
M Jimenez-Preitner, X Berney, M Uldry, A Vitali, S Cinti… - Cell metabolism, 2011 - cell.com
Brown adipocytes oxidize fatty acids to produce heat in response to cold or to excessive
energy intake; stimulation of brown fat development and function may thus counteract …
energy intake; stimulation of brown fat development and function may thus counteract …
An intercalation mechanism as a mode of action exerted by psychotropic drugs: results of altered phospholipid substrate availabilities in membranes?
R Oruch, A Lund, IF Pryme, H Holmsen - Journal of chemical biology, 2010 - Springer
Patients respond differently to psychotropic drugs, and this is currently a controversial theme
among psychiatrists. The effects of 16 psychotropics on cell membrane parameters have …
among psychiatrists. The effects of 16 psychotropics on cell membrane parameters have …
Molecular markers of preterm labor in the choriodecidua
R Shankar, MP Johnson, NA Williamson… - Reproductive …, 2010 - Springer
Because relevant biochemical changes are known to begin at the choriodecidual interface
some weeks before actual clinical onset of labor, we hypothesized that the preterm …
some weeks before actual clinical onset of labor, we hypothesized that the preterm …
Identification of phospholipid scramblase 1 as a biomarker and determination of its prognostic value for colorectal cancer
YB Kuo, CC Chan, CA Chang, CW Fan, RP Hung… - Molecular …, 2011 - Springer
The purpose of this study was to examine the expression of phospholipid scramblase 1
(PLSCR1) in tumor tissues and plasma specimens of patients with colorectal cancer (CRC) …
(PLSCR1) in tumor tissues and plasma specimens of patients with colorectal cancer (CRC) …
Genes with aberrant expression in murine preneoplastic intestine show epigenetic and expression changes in normal mucosa of colon cancer patients
D Leclerc, N Lévesque, Y Cao, L Deng, Q Wu… - Cancer Prevention …, 2013 - AACR
An understanding of early genetic/epigenetic changes in colorectal cancer would aid in
diagnosis and prognosis. To identify these changes in human preneoplastic tissue, we first …
diagnosis and prognosis. To identify these changes in human preneoplastic tissue, we first …
Phospholipid scramblase 1 is secreted by a lipid raft-dependent pathway and interacts with the extracellular matrix protein 1 in the dermal epidermal junction zone of …
J Merregaert, J Van Langen, U Hansen… - Journal of Biological …, 2010 - ASBMB
We examined the interaction of ECM1 (extracellular matrix protein 1) using yeast two-hybrid
screening and identified the type II transmembrane protein, PLSCR1 (phospholipid …
screening and identified the type II transmembrane protein, PLSCR1 (phospholipid …
PLSCR1/IP3R1/Ca2+ axis contributes to differentiation of primary AML cells induced by wogonoside
H Li, J Xu, Y Zhou, X Liu, Z Li, X Wang, Q Guo… - Cell Death & …, 2017 - nature.com
Multiple lines of evidence have demonstrated that increased expression of phospholipid
scramblase 1 (PLSCR1) is involved in the differentiation of acute myeloid leukemia (AML) …
scramblase 1 (PLSCR1) is involved in the differentiation of acute myeloid leukemia (AML) …
Silencing phospholipid scramblase 1 expression by RNA interference in colorectal cancer and metastatic liver cancer
W Cui, SY Li, JF Du, ZM Zhu, P An - Hepatobiliary & pancreatic diseases …, 2012 - Elsevier
Background Phospholipid scramblase 1 (PLSCR1) not only participates in the transbilayer
movement of phospholipids, but also plays a role in the pathogenesis and progression of …
movement of phospholipids, but also plays a role in the pathogenesis and progression of …
Identification of a putative transcriptome signature common to neuroblastoma and neural crest cells
M Angeles Rabadán, S Usieto… - Developmental …, 2013 - Wiley Online Library
Neuroblastoma, the most common extracranial tumor in children, is caused by genetic
lesions in neural crest precursors of the peripheral nervous system. However, since neural …
lesions in neural crest precursors of the peripheral nervous system. However, since neural …
Identification of PLSCR1 as a protein that interacts with RELT family members
Receptor expressed in lymphoid tissues (RELT) proteins are recently described surface
receptors belonging to the larger TNF receptor family. To improve our understanding of …
receptors belonging to the larger TNF receptor family. To improve our understanding of …