Vascular endothelial growth factors and receptors: anti-angiogenic therapy in the treatment of cancer
S Tugues, S Koch, L Gualandi, X Li… - Molecular aspects of …, 2011 - Elsevier
Vascular endothelial growth factors (VEGFs) are critical regulators of vascular and lymphatic
function during development, in health and in disease. There are five mammalian VEGF …
function during development, in health and in disease. There are five mammalian VEGF …
The role of the VEGF-C/VEGFRs axis in tumor progression and therapy
JC Chen, YW Chang, CC Hong, YH Yu… - International journal of …, 2012 - mdpi.com
Vascular endothelial growth factor C (VEGF-C) has been identified as a multifaceted factor
participating in the regulation of tumor angiogenesis and lymphangiogenesis. VEGF-C is not …
participating in the regulation of tumor angiogenesis and lymphangiogenesis. VEGF-C is not …
Tumor lymphangiogenesis as a potential therapeutic target
Metastasis the spread of cancer cells to distant organs, is the main cause of death for cancer
patients. Metastasis is often mediated by lymphatic vessels that invade the primary tumor …
patients. Metastasis is often mediated by lymphatic vessels that invade the primary tumor …
Chemotherapy or targeted therapy as second-line treatment of advanced gastric cancer. A systematic review and meta-analysis of published studies
Chemotherapy is a cornerstone in treatments of gastric cancer, but despite its benefit, less
than 60% of patients receive salvage therapy in clinical practice. We performed a systematic …
than 60% of patients receive salvage therapy in clinical practice. We performed a systematic …
An open-label, multicentre biomarker-oriented AIO phase II trial of sunitinib for patients with chemo-refractory advanced gastric cancer
Background Sunitinib monotherapy in pretreated patients with advanced gastric cancer
(AGC) was investigated. Preplanned analyses of tumour biomarkers on treatment outcome …
(AGC) was investigated. Preplanned analyses of tumour biomarkers on treatment outcome …
[HTML][HTML] Strategy for improved therapeutic efficiency of curcumin in the treatment of gastric cancer
M Jakubek, Z Kejík, R Kaplanek, R Hromadka… - Biomedicine & …, 2019 - Elsevier
Gastric cancer is a common oncological disease. Although enormous efforts have been
expended, possible therapeutic modalities are still limited. For this reason, new therapeutic …
expended, possible therapeutic modalities are still limited. For this reason, new therapeutic …
Lymphangiogenesis in gastric cancer regulated through Akt/mTOR-VEGF-C/VEGF-D axis
Background Lymphangiogenesis plays a significant role in metastasis and recurrence of
gastric cancer. There is no report yet focusing on the modulation of VEGF pathway and …
gastric cancer. There is no report yet focusing on the modulation of VEGF pathway and …
Roles of VEGF-C and Smad4 in the lymphangiogenesis, lymphatic metastasis, and prognosis in colon cancer
X Li, B Liu, J Xiao, Y Yuan, J Ma, Y Zhang - Journal of gastrointestinal …, 2011 - Elsevier
Abstract Background/Aims We combined two different signal pathways on transforming
growth factor β1 (TGF-β1)-Smad and vascular endothelial growth factor C (VEGF-C)/VEGF …
growth factor β1 (TGF-β1)-Smad and vascular endothelial growth factor C (VEGF-C)/VEGF …
[PDF][PDF] Roles of serum and biliary CEA, CA19-9, VEGFR3, and TAC in differentiating between malignant and benign biliary obstructions
ABSTRACT Background/Aims: Despite the presence of many diagnostic methods, the
differential diagnosis between benign and malignant biliary obstructions is still not easy. We …
differential diagnosis between benign and malignant biliary obstructions is still not easy. We …
Prognostic value of vascular endothelial growth factor expression in resected gastric cancer
Abstract Background and Aims: Vascular endothelial growth factor (VEGF) is a potential
prognostic biomarker for patients with resected gastric cancer. However, its role remains …
prognostic biomarker for patients with resected gastric cancer. However, its role remains …