Medulloblastoma: from myth to molecular
V Ramaswamy, MD Taylor - Journal of Clinical Oncology, 2017 - ascopubs.org
Current therapies for medulloblastoma were introduced primarily in the 1980s and consist of
predominantly cytotoxic, nontargeted approaches. Mortality from medulloblastoma remains …
predominantly cytotoxic, nontargeted approaches. Mortality from medulloblastoma remains …
Medulloblastoma: from molecular subgroups to molecular targeted therapies
Brain tumors are the leading cause of cancer-related death in children, and
medulloblastoma (MB) is the most common malignant pediatric brain tumor. Advances in …
medulloblastoma (MB) is the most common malignant pediatric brain tumor. Advances in …
Multicenter pilot study of radiochemotherapy as first-line treatment for adults with medulloblastoma (NOA-07)
Background Medulloblastoma in adult patients is rare, with 0.6 cases per million. Prognosis
depends on clinical factors and medulloblastoma entity. No prospective data on the …
depends on clinical factors and medulloblastoma entity. No prospective data on the …
Clinical trials in high-risk medulloblastoma: evolution of the SIOP-Europe HR-MB trial
S Bailey, N André, L Gandola, M Massimino… - Cancers, 2022 - mdpi.com
Simple Summary Patients with medulloblastoma receive treatment according to a risk
stratification, which is a combination of clinical and biological factors. To date there have …
stratification, which is a combination of clinical and biological factors. To date there have …
The clinical importance of medulloblastoma extent of resection: a systematic review
EM Thompson, A Bramall, JE Herndon… - Journal of Neuro …, 2018 - Springer
Background Although the majority of current medulloblastoma adjuvant therapy protocols
treat patients with≥ 1.5 cm 2 residual tumor as high risk with increased craniospinal …
treat patients with≥ 1.5 cm 2 residual tumor as high risk with increased craniospinal …
Posterior fossa tumors in children: current insights
While in adults most intracranial tumors develop around the cerebral hemispheres, 45 to
60% of pediatric lesions are found in the posterior fossa, although this anatomical region …
60% of pediatric lesions are found in the posterior fossa, although this anatomical region …
Management of high-risk medulloblastoma
E Bouffet - Neurochirurgie, 2021 - Elsevier
Medulloblastoma is the most common malignant brain tumors in children. Current
management combines surgery, radiotherapy, and chemotherapy. Current treatment of …
management combines surgery, radiotherapy, and chemotherapy. Current treatment of …
Evolution of systemic therapy in medulloblastoma including irradiation-sparing approaches
N Mushtaq, R Ul Ain, SA Hamid, E Bouffet - Diagnostics, 2023 - mdpi.com
The management of medulloblastoma in children has dramatically changed over the past
four decades, with the development of chemotherapy protocols aiming at improving survival …
four decades, with the development of chemotherapy protocols aiming at improving survival …
Questions and answers in the management of children with medulloblastoma over the time. How did we get here? A systematic review
MP Osuna-Marco, LI Martin-Lopez, AM Tejera… - Frontiers in …, 2023 - frontiersin.org
Introduction Treatment of children with medulloblastoma (MB) includes surgery, radiation
therapy (RT) and chemotherapy (CT). Several treatment protocols and clinical trials have …
therapy (RT) and chemotherapy (CT). Several treatment protocols and clinical trials have …
Cyclic metronomic chemotherapy for pediatric tumors: Six case reports and a review of the literature
B Carcamo, G Francia - Journal of Clinical Medicine, 2022 - mdpi.com
We report a retrospective case series of six Hispanic children with tumors treated with
metronomic chemotherapy. The six cases comprised one rhabdoid tumor of the kidney, one …
metronomic chemotherapy. The six cases comprised one rhabdoid tumor of the kidney, one …