Since the 1960s, paediatric oncologists have gradually become better organised in large
study groups and participation in clinical trials is today considered as the standard of care …

Children with medical complexity (CMC) have medical fragility and intensive care needs that
are not easily met by existing health care models. CMC may have a congenital or acquired …

AIM: Since the introduction of chemotherapy, survival in localised high-grade osteosarcoma
has improved considerably. However, there is still no worldwide consensus on a standard …

There has been enormous progress in the treatment of childhood cancer in the developed
world and the epidemiology in these countries is well described. Hitherto, there has been no …

BACKGROUND Fertility in adult life may be severely impaired by gonadotoxic therapies. For
young boys who do not yet produce spermatozoa, cryopreservation of immature testicular …

Background Childhood cancer survivors (CCSs) have an increased risk of morbidity and
mortality. We evaluated the prevalence and determinants of left ventricular (LV) dysfunction …

PURPOSE The histology of brain tumors determines treatment and predicts outcome.
Population-based survival reflects the effectiveness of a health care system in managing …

Background There is a concern regarding long‐term cognitive late effects after treatment for
acute lymphoblastic leukemia (ALL). The present study assessed neuropsychological …

STUDY QUESTION Does vitrification of human immature testicular tissue (ITT) have
potential benefits for future fertility preservation? Does vitrification of human ITT have …

Objectives: The aim of this study is to investigate parental emotional functioning during the
first five years of continuous remission after the end of their child's treatment and to identify …