Resistance profiles after different periods of exposure to a first-line antiretroviral regimen in a Cameroonian cohort of HIV type-1-infected patients
A Soria, K Porten, JC Fampou-Toundji… - Antiviral …, 2009 - journals.sagepub.com
Background The lack of HIV type-1 (HIV-1) viral load (VL) monitoring in resource-limited
settings might favour the accumulation of resistance mutations and thus hamper second-line …
settings might favour the accumulation of resistance mutations and thus hamper second-line …
The effect of temperature and moisture on the amorphous-to-crystalline transformation of stavudine
S Strydom, W Liebenberg, L Yu, M De Villiers - International journal of …, 2009 - Elsevier
Stavudine is a nucleoside reverse transcriptase inhibitor active against HIV, and is known to
exist in two polymorphic forms designated as forms I and II, and a hydrate form III. An …
exist in two polymorphic forms designated as forms I and II, and a hydrate form III. An …
High frequency of antiretroviral drug resistance among HIV-infected adults receiving first-line highly active antiretroviral therapy in N'Djamena, Chad
D Koyalta, C Charpentier, J Beassamda… - Clinical infectious …, 2009 - academic.oup.com
Antiretroviral drug resistance was evaluated in 88 adults infected with human
immunodeficiency virus, most with subtype CRF11_cpx, who had received a first-line …
immunodeficiency virus, most with subtype CRF11_cpx, who had received a first-line …
A retrospective survey of HIV drug resistance among patients 1 year after initiation of antiretroviral therapy at 4 clinics in Malawi
N Wadonda-Kabondo, BL Hedt… - Clinical infectious …, 2012 - academic.oup.com
In 2004, Malawi began scaling up its national antiretroviral therapy (ART) program. Because
of limited treatment options, population-level surveillance of acquired human …
of limited treatment options, population-level surveillance of acquired human …
Prevalence of HIV drug resistance before and 1 year after treatment initiation in 4 sites in the Malawi antiretroviral treatment program
N Wadonda-Kabondo, D Bennett… - Clinical infectious …, 2012 - academic.oup.com
Since 2004, the Malawi antiretroviral treatment (ART) program has provided a public health–
focused system based on World Health Organization clinical staging, standardized first-line …
focused system based on World Health Organization clinical staging, standardized first-line …
Using of nevirapine is associated with intermediate and reduced response to etravirine among HIV-infected patients who experienced virologic failure in a resource …
S Kiertiburanakul, S Wiboonchutikul, C Sukasem… - Journal of clinical …, 2010 - Elsevier
BACKGROUND: Non-nucleoside reverse transcriptase inhibitor (NNRTI)-based regimens
have been extensively used for treatment of HIV infection in resource-limited settings …
have been extensively used for treatment of HIV infection in resource-limited settings …
Genotypic impact of prolonged detectable HIV type 1 RNA viral load after HAART failure in a CRF01_AE-infected cohort
M Zolfo, JM Schapiro, V Phan, O Koole… - AIDS research and …, 2011 - liebertpub.com
HIV subtype-specific data on mutation type, rate, and accumulation following HAART
treatment failure are limited. We studied patterns and accrual of drug resistance mutations in …
treatment failure are limited. We studied patterns and accrual of drug resistance mutations in …
Evaluating the Role of Etravirine in the Second-Line Antiretroviral Therapy After Failing an Initial Non-Nucleoside Reverse Transcriptase Inhibitor-Based Regimen in a …
S Sungkanuparph, W Manosuthi… - Current HIV …, 2008 - ingentaconnect.com
Etravirine demonstrates activity against NNRTI-resistant HIV-1 but its efficacy depends on
the number of etravirine resistance-associated mutations (RAMs). This study aimed to …
the number of etravirine resistance-associated mutations (RAMs). This study aimed to …
Virological failure and HIV type 1 drug resistance profiles among patients followed-up in private sector, Douala, Cameroon
C Charpentier, F Talla, E Nguepi… - AIDS research and …, 2011 - liebertpub.com
The rate of virological failure was assessed in 819 patients followed up by the private sector
of Douala, the economic capital of Cameroon, and treated according to the World Health …
of Douala, the economic capital of Cameroon, and treated according to the World Health …
Control of M184V HIV-1 mutants by CD8 T-cell responses
T Vollbrecht, J Eberle, J Roider, S Bühler… - Medical microbiology …, 2012 - Springer
Antiretroviral treatment directed against HIV is highly effective, yet limited by drug resistance
mutations. We hypothesized that CD8 T cells targeting drug-resistant HIV mutants are able …
mutations. We hypothesized that CD8 T cells targeting drug-resistant HIV mutants are able …