Decorated bacteria and the application in drug delivery

F Wu, J Liu - Advanced Drug Delivery Reviews, 2022 - Elsevier
The use of living bacteria either as therapeutic agents or drug carriers has shown great
potential in treating a multitude of intractable diseases. However, cells are often fragile to …

Recent trends in cancer therapy: A review on the current state of gene delivery

EB Yahya, AM Alqadhi - Life Sciences, 2021 - Elsevier
Cancer treatment has been always considered one of the most critical and vital themes of
clinical issues. Many approaches have been developed, depending on the type and the …

Combined effects of host genetics and diet on human gut microbiota and incident disease in a single population cohort

Y Qin, AS Havulinna, Y Liu, P Jousilahti, SC Ritchie… - Nature Genetics, 2022 - nature.com
Human genetic variation affects the gut microbiota through a complex combination of
environmental and host factors. Here we characterize genetic variations associated with …

The role of the gut microbiome in colorectal cancer development and therapy response

L Sánchez-Alcoholado, B Ramos-Molina, A Otero… - Cancers, 2020 - mdpi.com
Colorectal cancer (CRC) is the third most common cancer worldwide and the leading cause
of cancer-related deaths. Recently, several studies have demonstrated that gut microbiota …

The molecular hallmarks of the serrated pathway in colorectal cancer

FDE De Palma, V D'argenio, J Pol, G Kroemer… - Cancers, 2019 - mdpi.com
Colorectal cancer (CRC) is a leading cause of cancer death worldwide. It includes different
subtypes that differ in their clinical and prognostic features. In the past decade, in addition to …

[HTML][HTML] The influence of the gut microbiota on the bioavailability of oral drugs

X Zhang, Y Han, W Huang, M Jin, Z Gao - Acta Pharmaceutica Sinica B, 2021 - Elsevier
Due to its safety, convenience, low cost and good compliance, oral administration attracts
lots of attention. However, the efficacy of many oral drugs is limited to their unsatisfactory …

Parvimonas micra, Peptostreptococcus stomatis, Fusobacterium nucleatum and Akkermansia muciniphila as a four-bacteria biomarker panel of colorectal cancer

MA Osman, H Neoh, NS Ab Mutalib, SF Chin… - Scientific Reports, 2021 - nature.com
Dysbiosis of the gut microbiome has been associated with the pathogenesis of colorectal
cancer (CRC). We profiled the microbiome of gut mucosal tissues from 18 CRC patients and …

Immune system, microbiota, and microbial metabolites: the unresolved triad in colorectal cancer microenvironment

M Hanus, D Parada-Venegas, G Landskron… - Frontiers in …, 2021 - frontiersin.org
Colorectal cancer (CRC) is one of the most common cancers worldwide. As with other
cancers, CRC is a multifactorial disease due to the combined effect of genetic and …

Streptococcus thermophilus inhibits colorectal tumorigenesis through secreting β-galactosidase

Q Li, W Hu, WX Liu, LY Zhao, D Huang, XD Liu… - Gastroenterology, 2021 - Elsevier
Background & Aims Streptococcus thermophilus was identified to be depleted in patients
with colorectal cancer (CRC) by shotgun metagenomic sequencing of 526 multicohort fecal …

Iron supplementation influence on the gut microbiota and probiotic intake effect in iron deficiency—A literature-based review

IG Rusu, R Suharoschi, DC Vodnar, CR Pop… - Nutrients, 2020 - mdpi.com
Iron deficiency in the human body is a global issue with an impact on more than two billion
individuals worldwide. The most important functions ensured by adequate amounts of iron in …