Cerebrospinal fluid in the diagnosis of multiple sclerosis: a consensus report.

M Andersson, J Alvarez-Cermeno… - Journal of Neurology …, 1994 - jnnp.bmj.com
The Committee of the European Concerted Action for Multiple Sclerosis (Charcot
Foundation) organised five workshops to discuss CSF analytical standards in the diagnosis …

The epidemiology of multiple sclerosis: insights to disease pathogenesis

DS Goodin - Handbook of clinical neurology, 2014 - Elsevier
The purpose of studying the epidemiology of multiple sclerosis (MS) is twofold. First, it is
important to understand clearly the natural history of the illness in order to assist patients in …

Recommended standard of cerebrospinal fluid analysis in the diagnosis of multiple sclerosis: a consensus statement

MS Freedman, EJ Thompson… - Archives of …, 2005 - jamanetwork.com
New criteria for the diagnosis of multiple sclerosis (MS) were published as the result of an
internationally formed committee. To increase the specificity of diagnosis and to minimize …

Acute disseminated encephalomyelitis, multiphasic disseminated encephalomyelitis and multiple sclerosis in children

RC Dale, C De Sousa, WK Chong, TCS Cox, B Harding… - Brain, 2000 - academic.oup.com
Forty-eight children with disseminated demyelination of the CNS, 28 with acute
disseminated encephalomyelitis (ADEM), seven with multiphasic disseminated …

Clinical and radiographic spectrum of pathologically confirmed tumefactive multiple sclerosis

CF Lucchinetti, RH Gavrilova, I Metz, JE Parisi… - Brain, 2008 - academic.oup.com
Atypical imaging features of multiple sclerosis lesions include size> 2 cm, mass effect,
oedema and/or ring enhancement. This constellation is often referred to as 'tumefactive …

B cells and antibodies in multiple sclerosis pathogenesis and therapy

M Krumbholz, T Derfuss, R Hohlfeld… - Nature Reviews …, 2012 - nature.com
B cells and antibodies account for the most prominent immunodiagnostic feature in patients
with multiple sclerosis (MS), namely oligoclonal bands. Furthermore, evidence is …

Isolated demyelinating syndromes: comparison of different MR imaging criteria to predict conversion to clinically definite multiple sclerosis

M Tintoré, A Rovira, MJ Martínez… - American Journal …, 2000 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Various authors have developed criteria to classify MR
imaging findings that suggest the possibility of multiple sclerosis. The purpose of this study …

The prognostic value of brain MRI in clinically isolated syndromes of the CNS. A 10-year follow-up.

JI O'riordan, AJ Thompson, DP Kingsley… - Brain: a journal of …, 1998 - academic.oup.com
A definitive diagnosis of multiple sclerosis cannot be made at presentation on patients with a
clinically isolated syndrome of the optic nerve, spinal cord or brainstem suggestive of …

The significance of brain magnetic resonance imaging abnormalities at presentation with clinically isolated syndromes suggestive of multiple sclerosis: a 5-year follow …

SP Morrissey, DH Miller, BE Kendall, DPE Kingsley… - Brain, 1993 - academic.oup.com
A 5-year follow-up study was performed on 89 patients who had undergone brain magnetic
resonance imaging (MRI) at presentation with an acute clinically isolated syndrome of the …

Intrathecal IgM synthesis is a prognostic factor in multiple sclerosis

LM Villar, J Masjuan… - Annals of Neurology …, 2003 - Wiley Online Library
Intrathecal IgM synthesis (ITMS) predicts a worse evolution in the first stages of multiple
sclerosis (MS). The aim of this study was the follow‐up of a group of relapsing‐remitting MS …