Aberrant B cell signaling plays a critical in role in various systemic and organ-specific
autoimmune diseases. This is supported by genetic evidence by many functional studies in …

Abstract Systemic Lupus Erythematosus is a systemic autoimmune disease characterized by
a great heterogenicity in course and clinical manifestations. Although prognosis improved in …

В настоящее время получены веские доказательства фундаментальной роли
патологической активации В-клеток в патогенезе иммуновоспалительных …

Improved characterization of relevant pathogenic pathways in systemic lupus erythematosus
(SLE) has been further delineated over the last decades. This led to the development of …

Owing to its systemic nature with multiple organs potentially being affected concurrently or
sequentially and at varying degrees of severity, the management of systemic lupus …

Lung involvement in systemic lupus erythematosus (SLE) and primary Sjögren's syndrome
(pSS) has extensively been outlined with a multiplicity of different manifestations. In SLE, the …

Aim. To assess the efficacy of belimumab in joint and skin manifestations in a nationwide
cohort of patients with SLE. Methods. All patients with skin and joint involvement enrolled in …

Aberrant B cell signaling plays a critical in role in various systemic and organ-specific
autoimmune diseases. This is supported by genetic evidence by many functional studies in …

目的快速评价贝利尤单抗治疗系统性红斑狼疮(SLE)/狼疮性肾炎(LN) 的安全性,
有效性和经济性, 为临床合理用药提供参考. 方法计算机检索Pubmed, Embase, the Cochrane …

目的探讨贝利尤单抗治疗难治性系统性红斑狼疮(systemic lupus erythematosus, SLE)
合并顽固性血液系统损害的疗效. 方法回顾性分析贵州省人民医院收治的1 例以顽固性血液系统 …