Fatigue is a complex phenomenon and an important health concern for many people with
chronic inflammatory rheumatic diseases, such as rheumatoid arthritis, psoriatic arthritis …

Sjögren syndrome is a phenotypically varied autoimmune disorder that can occur alone in
primary Sjögren syndrome or in association with other connective tissue diseases (CTDs) …

There is currently no approved treatment for primary Sjögren's syndrome, a disease that
primarily affects adult women. The difficulty in developing effective therapies is-in part …

Artificial intelligence (AI)-based predictive models are being used to foster a precision
medicine approach to treat complex chronic diseases such as autoimmune and …

Tumor necrosis factor receptor–associated factor 3 (TRAF3) is a central regulator of
immunity. TRAF3 is often somatically mutated in B cell malignancies, but its role in human …

Objective Although symptom relief is a critical aspect for successful drug development in
Sjögren's disease, patient experiences with Sjögren'srelated symptoms are understudied …

Background While all salivary glands (SGs) can be involved in primary Sjögren's syndrome
(pSS), their respective role in pathogenesis remains unclear. Our objective was to assess …

For many oncological conditions, the application of timely and patient-tailored targeted
therapies, or precision medicine, is a major therapeutic development that has provided …

Objective B cells are important in the pathogenesis of primary Sjögren's syndrome (pSS).
Patients positive for Sjögren's syndrome antigen A/Sjögren syndrome antigen B (SSA/SSB) …

Objective To assess the safety and efficacy of RSLV132, an RNase Fc fusion protein, in a
phase II randomized, doubleblind, placebocontrolled clinical trial in patients with primary …