Acute kidney injury (AKI) complicates recovery from cardiac surgery in up to 30% of patients,
injures and impairs the function of the brain, lungs, and gut, and places patients at a 5-fold …

Extracellular vesicles, such as exosomes and microvesicles, are host cell-derived packages
of information that allow cell–cell communication and enable cells to rid themselves of …

Mesenchymal stem cells form a population of self‐renewing, multipotent cells that can be
isolated from several tissues. Multiple preclinical studies have demonstrated that the …

Extracellular vesicles from the urine and circulation have gained significant interest as
potential diagnostic biomarkers in renal diseases. Urinary extracellular vesicles contain …

Abstract Background Mesenchymal stromal cells (MSCs) and renal stem/progenitors
improve the recovery of acute kidney injury (AKI) mainly through the release of paracrine …

Regenerative medicine relying on cell and gene therapies is one of the most promising
approaches to repair tissues. Multipotent mesenchymal stem/stromal cells (MSC), a …

Acute kidney injury (AKI), characterized by a sharp drop in glomerular filtration, continues to
be a significant health burden because it is associated with high initial mortality, morbidity …

Renal interstitial fibrosis (RIF) is an incurable pathological lesion in chronic kidney diseases.
Pericyte activation is the major pathological characteristic of RIF. Fibroblast and …

Cardiac surgery-associated acute kidney injury (CSA-AKI) is a common complication
following cardiac surgery and reflects a complex biological combination of patient pathology …

No real therapeutic modality is currently available for Acute kidney injury (AKI) and if any,
they are mainly supportive in nature. Therefore, developing a new therapeutic strategy is …