[HTML][HTML] Biological actions of curcumin on articular chondrocytes
Y Henrotin, AL Clutterbuck, D Allaway… - Osteoarthritis and …, 2010 - Elsevier
OBJECTIVES: Curcumin (diferuloylmethane) is the principal biochemical component of the
spice turmeric and has been shown to possess potent anti-catabolic, anti-inflammatory and …
spice turmeric and has been shown to possess potent anti-catabolic, anti-inflammatory and …
Interleukin-1 receptor antagonist (IL-1Ra) is more effective in suppressing cytokine-induced catabolism in cartilage-synovium co-culture than in cartilage monoculture
Background Most in vitro studies of potential osteoarthritis (OA) therapies have used
cartilage monocultures, even though synovium is a key player in mediating joint …
cartilage monocultures, even though synovium is a key player in mediating joint …
Scientific basis for the use of Indian ayurvedic medicinal plants in the treatment of neurodegenerative disorders: 1. Ashwagandha
MR Ven Murthy, PK Ranjekar… - … System Agents in …, 2010 - ingentaconnect.com
Ayurveda is a Sanskrit word, which means “the scripture for longevity”. It represents an
ancient system of traditional medicine prevalent in India and in several other south Asian …
ancient system of traditional medicine prevalent in India and in several other south Asian …
Chondrocyte senescence, joint loading and osteoarthritis.
JA Martin, TD Brown, AD Heiner… - … and Related Research …, 2004 - journals.lww.com
Abstract cellular level is not completely understood, but both aging and loading-induced
stresses have been shown to undermine cell functions related to the maintenance and …
stresses have been shown to undermine cell functions related to the maintenance and …
Impaired glucose transporter-1 degradation and increased glucose transport and oxidative stress in response to high glucose in chondrocytes from osteoarthritic …
SC Rosa, J Gonçalves, F Judas, A Mobasheri… - Arthritis research & …, 2009 - Springer
Introduction Disorders that affect glucose metabolism, namely diabetes mellitus (DM), may
favor the development and/or progression of osteoarthritis (OA). Thus far, little is known …
favor the development and/or progression of osteoarthritis (OA). Thus far, little is known …
Increased oxidative stress and its relation with collagen metabolism in knee osteoarthritis
The purpose of this study was to determine serum oxidative/antioxidative status in patients
with knee osteoarthritis and its relation with prolidase activity, which plays an important role …
with knee osteoarthritis and its relation with prolidase activity, which plays an important role …
Oxidative damage to extracellular matrix and its role in human pathologies
MD Rees, EC Kennett, JM Whitelock… - Free Radical Biology and …, 2008 - Elsevier
The extracellular compartments of most biological tissues are significantly less well
protected against oxidative damage than intracellular sites and there is considerable …
protected against oxidative damage than intracellular sites and there is considerable …
Anti-inflammatory and Anti-oxidant Properties of Curcuma longa (Turmeric) Versus Zingiber officinale (Ginger) Rhizomes in Rat Adjuvant-Induced Arthritis
G Ramadan, MA Al-Kahtani, WM El-Sayed - Inflammation, 2011 - Springer
Turmeric (rich in curcuminoids) and ginger (rich in gingerols and shogaols) rhizomes have
been widely used as dietary spices and to treat different diseases in Ayurveda/Chinese …
been widely used as dietary spices and to treat different diseases in Ayurveda/Chinese …
TLR2 signaling in chondrocytes drives calcium pyrophosphate dihydrate and monosodium urate crystal-induced nitric oxide generation
R Liu-Bryan, K Pritzker, GS Firestein… - The Journal of …, 2005 - journals.aai.org
Microcrystals of calcium pyrophosphate dihydrate (CPPD) and monosodium urate (MSU)
deposited in synovium and articular cartilage initiate joint inflammation and cartilage …
deposited in synovium and articular cartilage initiate joint inflammation and cartilage …
Endoplasmic reticulum stress and oxidative stress in inflammatory diseases
Y Tang, X Zhou, T Cao, E Chen, Y Li, W Lei… - DNA and Cell …, 2022 - liebertpub.com
Endoplasmic reticulum (ER) stress and oxidative stress (OS) are often related states in cells
as part of normal physiology but more frequently manifested in the pathophysiology of many …
as part of normal physiology but more frequently manifested in the pathophysiology of many …