Voltage-gated sodium channels as insecticide targets

KS Silver, Y Du, Y Nomura, EE Oliveira… - Advances in insect …, 2014 - Elsevier
Voltage-gated sodium channels are critical for the generation and propagation of action
potentials. They are the primary target of several classes of insecticides, including DDT …

Molecular biology of insect sodium channels and pyrethroid resistance

K Dong, Y Du, F Rinkevich, Y Nomura, P Xu… - Insect biochemistry and …, 2014 - Elsevier
Voltage-gated sodium channels are essential for the initiation and propagation of the action
potential in neurons and other excitable cells. Because of their critical roles in electrical …

Molecular mechanism of action and selectivity of sodium ch annel blocker insecticides

K Silver, K Dong, BS Zhorov - Current medicinal chemistry, 2017 - ingentaconnect.com
Sodium channel blocker insecticides (SCBIs) are a relatively new class of insecticides that
are represented by two commercially registered compounds, indoxacarb and …

Two novel sodium channel mutations associated with resistance to indoxacarb and metaflumizone in the diamondback moth, Plutella xylostella

XL Wang, W Su, JH Zhang, YH Yang, K Dong… - Insect …, 2016 - Wiley Online Library
Indoxacarb and metaflumizone belong to a relatively new class of sodium channel blocker
insecticides (SCBIs). Due to intensive use of indoxacarb, field‐evolved indoxacarb …

Metabolic and Behavioral Mechanisms of Indoxacarb Resistance in Sitophilus zeamais (Coleoptera: Curculionidae)

K Haddi, LP Mendonça, MF Dos Santos… - Journal of Economic …, 2015 - academic.oup.com
The control of the most important pest of stored maize, the weevil Sitophilus zeamais
Motschulsky (Coleoptera: Curculionidae), is mainly achieved with the use of pyrethroid …

Mechanism of action of sodium channel blocker insecticides (SCBIs) on insect sodium channels

KS Silver, W Song, Y Nomura, VL Salgado… - Pesticide biochemistry …, 2010 - Elsevier
Sodium channel blocker insecticides (SCBIs) are a relatively new class of insecticides, with
a mechanism of action different from those of other classes of insecticides that target voltage …

Indoxacarb resistance-associated mutation of Liriomyza trifolii in Hainan, China

F Li, X Gong, L Yuan, X Pan, H Jin, R Lu… - Pesticide Biochemistry and …, 2022 - Elsevier
Liriomyza trifolii, which has been recently prevalent in China, harms more than 300 plant
species, especially cowpea in Hainan. This pest also affects the quality and production of …

Indoxacarb, metaflumizone, and other sodium channel inhibitor insecticides: mechanism and site of action on mammalian voltage-gated sodium channels

RT von Stein, KS Silver, DM Soderlund - Pesticide biochemistry and …, 2013 - Elsevier
Sodium channel inhibitor (SCI) insecticides were discovered almost four decades ago but
have only recently yielded important commercial products (eg, indoxacarb and …

[HTML][HTML] Synergists action of piperonyl butoxide and S, S, S-tributyl phosphorotrithioate on toxicity of carbamate insecticides against Blattella germanica

AS Dehkordi, YS Abadi, H Nasirian, T Hazratian… - Asian Pacific Journal of …, 2017 - Elsevier
Objective To determine the synergists action of piperonyl butoxide (PBO) and S, S, S-tributyl
phosphorotrithioate (DEF) on toxicity of carbamate insecticides against Blattella germanica …

The receptor site and mechanism of action of sodium channel blocker insecticides

Y Zhang, Y Du, D Jiang, C Behnke, Y Nomura… - Journal of Biological …, 2016 - ASBMB
Sodium channels are excellent targets of both natural and synthetic insecticides with high
insect selectivity. Indoxacarb, its active metabolite DCJW, and metaflumizone (MFZ) belong …