This review gives an overview of recent findings and developments in research on brain
mechanisms of reward and reinforcement from studies using the place preference …

Much research supports a link between stress and its concomitant hypothalamic–pituitary–
adrenal (HPA) axis responses with behavioral sensitivity to psychoactive drugs. Our …

The present experiment examined the contribution of locomotor response to novelty and
prior exposure to amphetamine to rats' predisposition to self-administer a low dose of the …

To study the role of glutamate in cocaine‐conditioned responses, we developed a rat model
in which conditioned locomotion is produced by repeated pairing of cocaine with discrete …

Heading Abstract Rationale. The study of individual differences in drug addiction may have
important implications both for understanding the etiology of addiction and for strategies for …

In parallel with nucleus accumbens (NAS), ventral pallidum (VP) also receives a
dopaminergic projection from the ventral tegmental area (VTA). The present study examined …

Novelty-seeking in rodents, defined as enhanced specific exploration of novel situations, is
considered to predict the response of animals to drugs of abuse and, thus, identify “drug …

Rationale and objectives Our previous work uncovered a differential preference of maternal
female rats for cues associated with pups versus cues associated with cocaine at three …

Individual differences in locomotor responses to novelty and psychostimulants, and
sensitization following repeated drug exposure, predict increased sensitivity to the …

Previous research has shown that a rat's level of activity in a novel environment can predict
the strength of amphetamine-induced locomotor behavior and self-administration, but not …