A comprehensive literature review and expert consensus statement on therapeutic drug monitoring of biologics in inflammatory bowel disease
Therapeutic drug monitoring (TDM) of biologics is a rapidly evolving field. We aimed to
provide a consensus statement regarding the clinical utility of TDM for biologics in …
provide a consensus statement regarding the clinical utility of TDM for biologics in …
[HTML][HTML] Appropriate therapeutic drug monitoring of biologic agents for patients with inflammatory bowel diseases
Background & Aims Therapeutic drug monitoring (TDM) is widely available for biologic
therapies in patients with inflammatory bowel disease (IBD). We reviewed current data and …
therapies in patients with inflammatory bowel disease (IBD). We reviewed current data and …
ECCO guidelines on therapeutics in ulcerative colitis: medical treatment
Ulcerative colitis [UC] is a chronic inflammatory bowel disease [IBD] characterised by colonic
inflammation extending to a variable extent from the rectum. Care of the patient with UC …
inflammation extending to a variable extent from the rectum. Care of the patient with UC …
Therapeutic drug monitoring of biologics in inflammatory bowel disease: unmet needs and future perspectives
Therapeutic drug monitoring (TDM) has emerged as a useful tool for optimising the use of
biologics, and in particular anti-tumour necrosis factor (anti-TNF) therapy, in inflammatory …
biologics, and in particular anti-tumour necrosis factor (anti-TNF) therapy, in inflammatory …
Therapeutic drug monitoring with biologic agents in immune mediated inflammatory diseases
K Papamichael, EH Vogelzang, J Lambert… - Expert review of …, 2019 - Taylor & Francis
Introduction: Biologic therapy has revolutionized the treatment of immune mediated
inflammatory diseases (IMID), such as inflammatory bowel disease (IBD), rheumatoid and …
inflammatory diseases (IMID), such as inflammatory bowel disease (IBD), rheumatoid and …
How, when, and for whom should we perform therapeutic drug monitoring?
S Vermeire, E Dreesen, K Papamichael… - Clinical …, 2020 - Elsevier
The implementation of therapeutic drug monitoring (TDM) in the inflammatory bowel disease
practice has evolved over the years. In the early days, the focus was merely on measuring …
practice has evolved over the years. In the early days, the focus was merely on measuring …
Therapeutic drug monitoring of biologics during induction to prevent primary non-response
MP Sparrow, K Papamichael, MG Ward… - Journal of Crohn's …, 2020 - academic.oup.com
Biologic therapies have revolutionized the management of inflammatory bowel disease
[IBD], but primary and secondary non-responses occur in a significant proportion of patients …
[IBD], but primary and secondary non-responses occur in a significant proportion of patients …
Transitioning from intravenous to subcutaneous vedolizumab in patients with inflammatory bowel disease [TRAVELESS]
E Ventress, D Young, S Rahmany… - Journal of Crohn's …, 2022 - academic.oup.com
Abstract Background and Aims Subcutaneous [SC] vedolizumab presents the opportunity for
inflammatory bowel disease [IBD] patients to manage their treatment at home. There are …
inflammatory bowel disease [IBD] patients to manage their treatment at home. There are …
Residual homing of α4β7-expressing β1+ PI16+ regulatory T cells with potent suppressive activity correlates with exposure-efficacy of vedolizumab
E Becker, M Dedden, C Gall, M Wiendl, AB Ekici… - Gut, 2022 - gut.bmj.com
Objective The anti-α4β7 integrin antibody vedolizumab is administered at a fixed dose for
the treatment of IBDs. This leads to a wide range of serum concentrations in patients and …
the treatment of IBDs. This leads to a wide range of serum concentrations in patients and …
Comparison of short‐and long‐term effectiveness between ustekinumab and vedolizumab in patients with Crohn's disease refractory to anti‐tumour necrosis factor …
L Manlay, G Boschetti, B Pereira… - Alimentary …, 2021 - Wiley Online Library
Background The best option between vedolizumab and ustekinumab after anti‐tumour
necrosis factor (TNF) failure remains unclear in Crohn's disease. Aims To compare the short …
necrosis factor (TNF) failure remains unclear in Crohn's disease. Aims To compare the short …