[HTML][HTML] Mesenchymal stromal/stem cell (MSC)-derived exosomes in clinical trials
A Lotfy, NM AboQuella, H Wang - Stem Cell Research & Therapy, 2023 - Springer
Mesenchymal stromal/stem cells (MSCs) are widely utilized in cell therapy because of their
robust immunomodulatory and regenerative properties. Their paracrine activity is one of the …
robust immunomodulatory and regenerative properties. Their paracrine activity is one of the …
[HTML][HTML] Therapeutic nanoparticles and their targeted delivery applications
Nanotechnology offers many advantages in various fields of science. In this regard,
nanoparticles are the essential building blocks of nanotechnology. Recent advances in …
nanoparticles are the essential building blocks of nanotechnology. Recent advances in …
[HTML][HTML] Exosomes from TNF-α-treated human gingiva-derived MSCs enhance M2 macrophage polarization and inhibit periodontal bone loss
Mesenchymal stem cell (MSC)–derived exosome plays a central role in the cell-free
therapeutics involving MSCs and the contents can be customized under disease-associated …
therapeutics involving MSCs and the contents can be customized under disease-associated …
Umbilical cord-derived mesenchymal stem cell-derived exosomes combined pluronic F127 hydrogel promote chronic diabetic wound healing and complete skin …
J Yang, Z Chen, D Pan, H Li, J Shen - International journal of …, 2020 - Taylor & Francis
Purpose Chronic refractory wounds are a multifactorial comorbidity of diabetes mellitus with
the characteristic of impaired vascular networks. Currently, there is a lack of effective …
the characteristic of impaired vascular networks. Currently, there is a lack of effective …
[HTML][HTML] Melatonin-stimulated MSC-derived exosomes improve diabetic wound healing through regulating macrophage M1 and M2 polarization by targeting the PTEN …
W Liu, M Yu, D Xie, L Wang, C Ye, Q Zhu, F Liu… - Stem cell research & …, 2020 - Springer
Background After surgery, wound recovery in diabetic patients may be disrupted due to
delayed inflammation, which can lead to undesired consequences, and there is currently a …
delayed inflammation, which can lead to undesired consequences, and there is currently a …
Mesenchymal stem cell-derived exosomes for clinical use
M Mendt, K Rezvani, E Shpall - Bone marrow transplantation, 2019 - nature.com
Mesenchymal stem/stromal cells (MSCs) are commonly used as a source of cellular therapy
due to their strong immunosuppressive and regenerative effects. One of the key …
due to their strong immunosuppressive and regenerative effects. One of the key …
Bone‐a‐petite: engineering exosomes towards bone, osteochondral, and cartilage repair
Recovery from bone, osteochondral, and cartilage injuries/diseases has been burdensome
owing to the damaged vasculature of large defects and/or avascular nature of cartilage …
owing to the damaged vasculature of large defects and/or avascular nature of cartilage …
Microenvironment‐protected exosome‐hydrogel for facilitating endometrial regeneration, fertility restoration, and live birth of offspring
J Lin, Z Wang, J Huang, S Tang, Q Saiding, Q Zhu… - Small, 2021 - Wiley Online Library
Thin endometrium is a primary cause of failed embryo transfer, resulting in long‐term
infertility and negative family outcomes. While hormonal treatments have greatly improved …
infertility and negative family outcomes. While hormonal treatments have greatly improved …
Advances in extracellular vesicle nanotechnology for precision theranostics
Q Wu, S Fu, H Xiao, J Du, F Cheng, S Wan… - Advanced …, 2023 - Wiley Online Library
Extracellular vesicles (EVs) have increasingly been recognized as important cell surrogates
influencing many pathophysiological processes, including cellular homeostasis, cancer …
influencing many pathophysiological processes, including cellular homeostasis, cancer …
[HTML][HTML] Exosomes from adipose-derived stem cells regulate M1/M2 macrophage phenotypic polarization to promote bone healing via miR-451a/MIF
R Li, D Li, H Wang, K Chen, S Wang, J Xu… - Stem cell research & …, 2022 - Springer
Objectives Bone defects caused by diseases and trauma are usually accompanied by
inflammation, and the implantation of biomaterials as a common repair method has also …
inflammation, and the implantation of biomaterials as a common repair method has also …