Adipose tissue produces factors, including adipokines, cytokines and chemokines which,
when released, systemically exert endocrine effects on multiple tissues thereby affecting …

BACKGROUND Puberty is a complex developmental event, controlled by sophisticated
regulatory networks that integrate peripheral and internal cues and impinge at the brain …

Most endocrine systems in the body are influenced by the hypothalamic-pituitary axis. Within
this axis, the hypothalamus delivers precise signals to the pituitary gland, which in turn …

Kisspeptin (Kiss1) neurons are essential for reproduction, but their role in the control of
energy balance and other homeostatic functions remains unclear. Proopiomelanocortin …

Reproduction in mammals is an extremely energy-intensive process and is therefore tightly
controlled by the body's energy status. Changes in the nutritional status of the body cause …

STUDY QUESTION Do cerebrospinal fluid (CSF) concentrations of gamma-aminobutyric
acid (GABA), testosterone (T) and estradiol (E2) differ in women with polycystic ovary …

Apart from the well-established role of kisspeptin (Kp) in the regulation of reproductive
functions, recent data described its action in the control of metabolism. Of particular interest …

The control of reproductive processes involves the integration of a number of factors from the
internal and external environment, with the final output signal of these processes being the …

Introduction: The onset of puberty in females is highly sensitive to the nutritional status and
the amount of energy reserves of the organism. This metabolic information is sensed and …

Polycystic ovary syndrome (PCOS) is a complex endocrine disease that can cause female
infertility and bring economic burden to families and to society. The clinical and/or …