Liquid biopsies, in particular, analysis of cell-free DNA (cfDNA), have emerged as a
promising noninvasive diagnostic approach in oncology. Abnormal distribution of DNA …

High-throughput sequencing, also known as next-generation sequencing (NGS), has
revolutionized genomic research. In recent years, NGS technology has steadily improved …

The high-throughput-next generation sequencing (HT-NGS) technologies are currently the
hottest topic in the field of human and animals genomics researches, which can produce …

Human cancer cell lines are an integral part of drug discovery practices. However, modeling
the complexity of cancer utilizing these cell lines on standard plastic substrata, does not …

Elevated levels of both reactive oxygen species (ROS) and DNA methylation are
characteristic of various types of cancer cells. However, the relation between these two is not …

The complex pathobiology underlying cardiovascular diseases (CVDs) has yet to be
explained. Aberrant epigenetic changes may result from alterations in enzymatic activities …

Nucleotide variants, especially those related to epigenetic functions, provide critical
regulatory information beyond simple genomic sequence, and they define cell status in …

Although the factors responsible for the recent increase in the prevalence of diabetes
worldwide are not entirely known, the morbidity associated with this disease results in …

Epigenetic modifications control chromatin structure and function, and thus mediate changes
in gene expression, ultimately influencing protein levels. Recent research indicates that …

Epidemiology is the branch of science that investigates the causes and distribution of
disease in populations in order to provide preventative measures and promote human …