The role of primary tumour sidedness, EGFR gene copy number and EGFR promoter methylation in RAS/BRAF wild-type colorectal cancer patients receiving …
L Demurtas, M Puzzoni, R Giampieri, P Ziranu… - British Journal of …, 2017 - nature.com
Background: The data from randomised trials suggested that primary tumour sidedness
could represent a prognostic and predictive factor in colorectal cancer (CRC) patients …
could represent a prognostic and predictive factor in colorectal cancer (CRC) patients …
Identification of an individualized therapy prognostic signature for head and neck squamous cell carcinoma
C Lin, Y Chen, J Pan, Q Lu, P Ji, S Lin, C Liu, S Lin… - BMC genomics, 2023 - Springer
Background Head and neck squamous cell carcinoma (HNSCC) are the most common
cancers in the head and neck. Therapeutic response-related genes (TRRGs) are closely …
cancers in the head and neck. Therapeutic response-related genes (TRRGs) are closely …
Functional suppression of epiregulin impairs angiogenesis and aggravates left ventricular remodeling by disrupting the extracellular‐signal‐regulated kinase1/2 …
Y Cai, KL Xie, HL Wu, K Wu - Journal of Cellular Physiology, 2019 - Wiley Online Library
Acute myocardial infarction (AMI), a severe consequence of coronary atherosclerotic heart
disease, is often associated with high mortality and morbidity. Emerging evidence have …
disease, is often associated with high mortality and morbidity. Emerging evidence have …
High EREG expression is predictive of better outcomes in rectal cancer patients receiving neoadjuvant concurrent chemoradiotherapy
CY Lin, PL Hsieh, CL Chou, CC Yang, SW Lee… - Oncology, 2020 - karger.com
Background/Aim: A great proportion of patients with rectal cancer initially present with locally
advanced disease and can potentially benefit from neoadjuvant concurrent …
advanced disease and can potentially benefit from neoadjuvant concurrent …
A modified MethyLight assay predicts the clinical outcomes of anti‐epidermal growth factor receptor treatment in metastatic colorectal cancer
K Ouchi, S Takahashi, A Okita, Y Sakamoto… - Cancer …, 2022 - Wiley Online Library
DNA methylation status correlates with clinical outcomes of anti‐epidermal growth factor
receptor (EGFR) treatment. There is a strong need to develop a simple assay for measuring …
receptor (EGFR) treatment. There is a strong need to develop a simple assay for measuring …
Hypermethylation of N-Acetyltransferase 1 Is a Prognostic Biomarker in Colon Adenocarcinoma
C Shi, L Xie, Y Tang, L Long, J Li, B Hu, K Li - Frontiers in Genetics, 2019 - frontiersin.org
Background: The N-acetyltransferase 1 (NAT1) gene is downregulated in several cancers
and associated with patient survival. In this study, we sought to examine the prognostic …
and associated with patient survival. In this study, we sought to examine the prognostic …
Biomarker-driven and molecular targeted therapies for colorectal cancers
M Schirripa, SA Cohen, F Battaglin, HJ Lenz - Seminars in oncology, 2018 - Elsevier
Improved clinical selection and identification of new molecules and innovative strategies
have widened treatment options and increased overall survival in metastatic colorectal …
have widened treatment options and increased overall survival in metastatic colorectal …
[HTML][HTML] Synchronous and metachronous colorectal liver metastases: impact of primary tumor location on patterns of recurrence and survival after hepatic resection
I Garajova, R Balsano, C Tommasi… - Acta Bio Medica …, 2021 - ncbi.nlm.nih.gov
Background: Considerable differences in terms of prognosis exist between the right-sided
(RCC) and the left-sided colon cancer (LCC). Aim of the work: In this study, we evaluated …
(RCC) and the left-sided colon cancer (LCC). Aim of the work: In this study, we evaluated …
Embryonic origin of primary colon cancer predicts survival in patients undergoing ablation for colorectal liver metastases
Background In patients with primary colorectal cancer (CRC) or unresectable metastatic
CRC, midgut embryonic origin is associated with worse prognosis. The impact of embryonic …
CRC, midgut embryonic origin is associated with worse prognosis. The impact of embryonic …
FOLFOX plus anti-epidermal growth factor receptor (EGFR) monoclonal antibody (mAb) is an effective first-line treatment for patients with RAS-wild left-sided …
D Chen, L Li, X Zhang, G Gao, L Shen, J Hu, M Yang… - Medicine, 2018 - journals.lww.com
Background: The efficacy of oxaliplatin-based chemotherapy combined with anti-epidermal
growth factor receptor (EGFR) monoclonal antibody (mAb) remains controversial in …
growth factor receptor (EGFR) monoclonal antibody (mAb) remains controversial in …