The toxic side effects of early generations of red blood cell substitutes have stimulated
development of more safe and efficacious high-molecular-weight polymerized hemoglobins …

The search for a clinically affordable substitute of human blood for transfusion is still an
unmet need of modern society. More than 50 years of research on acellular hemoglobin …

Until today, artificial oxygen carriers have not been reached satisfactory quality for routine
clinical treatments. To bridge this gap, we designed albumin-derived perfluorocarbon-based …

Os procedimentos necessários para redução de efeitos adversos associados à transfusão
de sangue, em especial aqueles decorrentes da transmissão de agentes infecciosos e da …

Compositions of matter and methods for making, storing and administering artificial blood
substitutes. Artificial blood Substitutes may have oxygen carriers that encapsulate an oxy …

Perftoran is a perfluorocarbon emulsion developed in Russia, with a similar composition to
Fluosol. Perftoran is stabilized with Proxanol P 268 instead of Pluronic F-68, both of which …

Blood transfusion is the second most used medical procedures in health care systems
worldwide. Over the last few decades, significant changes have been evolved in transfusion …

There is much interest in the use of nanoparticles as targeted contrast agents, biosensors,
targeted drug delivery vehicles, and as artificial oxygen carrieres. Nanoparticles of interest …

The objective of this study was to develop an effective and reliable cellular hemoglobin-
based blood substitute (HBOC). Cellular HBOCs were created by encapsulating bovine …

Die Entwicklung von künstlichem Blut bzw. künstlichen Sauerstoffträgern begann schon
während des zweiten Weltkrieges. Das damals besonders hohe Aufkommen an …