Human papillomaviruses modulate microRNA 145 expression to directly control genome amplification

V Gunasekharan, LA Laimins - Journal of virology, 2013 - Am Soc Microbiol
Human papillomaviruses (HPVs) modulate expression of host microRNAs. Our deep-
sequencing analysis of organotypic raft cultures identified microRNA 145 (miR-145) as a …

miR-375 activates p21 and suppresses telomerase activity by coordinately regulating HPV E6/E7, E6AP, CIP2A, and 14-3-3ζ

HM Jung, BL Phillips, EKL Chan - Molecular cancer, 2014 - Springer
Abstract Background While microRNAs (miRNAs) are extensively studied in post-
transcriptional regulation of gene expressions in many biological processes, cellular miRNA …

MiRNA biomarkers in cancers of the male reproductive system: are we approaching clinical application?

V Constâncio, NT Tavares, R Henrique… - …, 2023 - Wiley Online Library
Background Specific cancer types face specific clinical management challenges. Owing to
their stability, robustness and fast, easy and cost‐effective detection, microRNAs (miRNAs) …

HPV-associated cancers: insights into the mechanistic scenario and latest updates

AG Mukherjee, U Ramesh Wanjari… - Medical Oncology, 2023 - Springer
Cancer and related diseases are the second leading cause of death worldwide. The human
papillomavirus (HPV) is an infectious agent that can be spread mainly through sexual …

Current status of human papillomavirus-related head and neck cancer: from viral genome to patient care

H Dong, X Shu, Q Xu, C Zhu, AM Kaufmann, ZM Zheng… - Virologica Sinica, 2021 - Springer
Human papillomavirus (HPV) infection identified as a definitive human carcinogen is
increasingly being recognized for its role in carcinogenesis of human cancers. Up to 38 …

Molecular targets of HPV oncoproteins: potential biomarkers for cervical carcinogenesis

AC de Freitas, EC Coimbra, MCG Leitão - Biochimica et Biophysica Acta …, 2014 - Elsevier
Cervical cancer is the second most common cancer among women worldwide and is
responsible for 275,000 deaths each year. Persistent infection with high-risk human …

[HTML][HTML] MicroRNA-27b up-regulated by human papillomavirus 16 E7 promotes proliferation and suppresses apoptosis by targeting polo-like kinase2 in cervical …

F Liu, S Zhang, Z Zhao, X Mao, J Huang, Z Wu… - Oncotarget, 2016 - ncbi.nlm.nih.gov
The infection with high-risk human papillomavirus is linked to cervical cancer, nevertheless,
the role of miRNAs regulated by HPV oncogenes in cancer progression remain largely …

Glucocorticoid regulation of a novel HPV–E6–p53–miR‐145 pathway modulates invasion and therapy resistance of cervical cancer cells

M Shi, L Du, D Liu, L Qian, M Hu, M Yu… - The Journal of …, 2012 - Wiley Online Library
Glucocorticoids are stress‐responsive neuroendocrine mediators and play an important role
in malignant progression, especially in solid tumours. We demonstrate a novel mechanism …

Smoking and microRNA dysregulation: a cancerous combination

N Momi, S Kaur, S Rachagani, AK Ganti… - Trends in molecular …, 2014 - cell.com
MicroRNAs (miRNAs) are post-transcriptional gene regulators that are differentially
expressed in several pathophysiological conditions including cancer. They impact the …

Transcription addiction: can we garner the Yin and Yang functions of E2F1 for cancer therapy?

P Meng, R Ghosh - Cell death & disease, 2014 - nature.com
Classically, as a transcription factor family, the E2Fs are known to regulate the expression of
various genes whose products are involved in a multitude of biological functions, many of …