Background Microbial invasion of the amniotic cavity resulting in intra-amniotic infection is
associated with obstetrical complications such as preterm labor with intact or ruptured …

STUDY QUESTION How does hormonal contraceptive use and menstrual cycle phase affect
the female microbiome across different body sites? SUMMARY ANSWER The menstrual …

Abstract Analysis of metagenomic and metatranscriptomic data is complicated and typically
requires extensive computational resources. Leveraging a curated reference database of …

Non-optimal vaginal microbiota, as observed in bacterial vaginosis (BV), is typically
characterized by a depletion of beneficial lactobacilli and an abundance of numerous …

Background Vaginal dysbiosis covers imbalances in the vaginal microbiota, defined by
altered composition of bacteria, viruses, and fungi and is associated with euploid pregnancy …

The maternal microbiome is essential for the healthy growth and development of offspring
and has long-term effects later in life. Recent advances indicate that the maternal …

The female reproductive tract harbors a unique microbiome, especially the vagina. The
human vaginal microbiome exhibits a low diversity and is dominated by Lactobacillus …

Background Preterm premature rupture of membranes (PPROM), which is associated with
vaginal dysbiosis, is responsible for up to one-third of all preterm births. Consecutive …

Emerging evidence demonstrates that alterations to the gut microbiota can affect mood,
suggesting that the microbiota–gut–brain (MGB) axis contributes to the pathogenesis of …

Regulatory T cells (Tregs) have been exhaustively investigated during early pregnancy;
however, their role later in gestation is poorly understood. Herein, we report that functional …