Fluorescent protein lifetimes report densities and phases of nuclear condensates during embryonic stem-cell differentiation

K Joron, JO Viegas, L Haas-Neill, S Bier, P Drori… - Nature …, 2023 - nature.com
Fluorescent proteins (FP) are frequently used for studying proteins inside cells. In advanced
fluorescence microscopy, FPs can report on additional intracellular variables. One variable …

Approaches to characterize chromatin subcompartment organization in the cell nucleus

R Weinmann, L Frank, K Rippe - Current Opinion in Structural Biology, 2023 - Elsevier
The mechanism of self-organization of chromatin subcompartments on the 0.1–1 μm scale
and their impact on genome-associated activities has long been a key aspect of research on …

Histone 4 lysine 20 tri-methylation: a key epigenetic regulator in chromatin structure and disease

A Agredo, AL Kasinski - Frontiers in Genetics, 2023 - frontiersin.org
Chromatin is a vital and dynamic structure that is carefully regulated to maintain proper cell
homeostasis. A great deal of this regulation is dependent on histone proteins which have the …

Multi-scale imaging of the dynamic organization of chromatin

F García Fernández, S Huet, J Miné-Hattab - International Journal of …, 2023 - mdpi.com
Chromatin is now regarded as a heterogeneous and dynamic structure occupying a non-
random position within the cell nucleus, where it plays a key role in regulating various …

Mode of SUV420H2 heterochromatin localization through multiple HP1 binding motifs in the heterochromatic targeting module

M Nakao, Y Sato, A Aizawa, H Kimura - Genes to Cells, 2024 - Wiley Online Library
Constitutive heterochromatin is transcriptionally repressed and densely packed chromatin,
typically harboring histone H3 Lys9 trimethylation (H3K9me3) and heterochromatin protein 1 …

[PDF][PDF] Structural Biology

R Weinmann, L Frank, K Rippe - Current …, 2023 - malone.bioquant.uni-heidelberg.de
The mechanism of self-organization of chromatin subcompartments on the 0.1–1 μm scale
and their impact on genomeassociated activities has long been a key aspect of research on …

Fluorescent protein lifetimes report increased local densities and phases of nuclear condensates during embryonic stem cell differentiation

K Joron, JO Viegas, L Haas-Neill, S Bier, P Drori, S Dvir… - bioRxiv, 2023 - biorxiv.org
Fluorescent proteins (FP) are frequently used for studying proteins inside cells. In advanced
fluorescence microscopy, FPs can report on additional intracellular variables. One variable …

[HTML][HTML] Nuclear Control of Cell Proliferation

D Fisher - igmm.cnrs.fr
Cell proliferation is important for health, but when uncontrolled it often leads to cancer.
Cyclin-dependent kinases (CDKs) are key regulators of cell proliferation, and they trigger …

[HTML][HTML] Contrôle Nucléaire de la Prolifération Cellulaire

D Fisher - igmm.cnrs.fr
Cell proliferation is important for health, but when uncontrolled it often leads to cancer.
Cyclin-dependent kinases (CDKs) are key regulators of cell proliferation, and they trigger …