Dopamine and T cells: dopamine receptors and potent effects on T cells, dopamine production in T cells, and abnormalities in the dopaminergic system in T cells in …

M Levite - Acta physiologica, 2016 - Wiley Online Library
Dopamine, a principal neurotransmitter, deserves upgrading to 'NeuroImmunotransmitter'
thanks to its multiple, direct and powerful effects on most/all immune cells. Dopamine by …

The dopamine transporter: An unrecognized nexus for dysfunctional peripheral immunity and signaling in Parkinson's Disease

P Mackie, J Lebowitz, L Saadatpour, E Nickoloff… - Brain, behavior, and …, 2018 - Elsevier
The second-most common neurodegenerative disease, Parkinson's Disease (PD) has three
hallmarks: dysfunctional dopamine transmission due, at least in part, to dopamine neuron …

Dopamine receptor D3 expressed on CD4+ T cells favors neurodegeneration of dopaminergic neurons during Parkinson's disease

H González, F Contreras, C Prado… - The Journal of …, 2013 - journals.aai.org
Emerging evidence has demonstrated that CD4+ T cells infiltrate into the substantia nigra
(SN) in Parkinson's disease (PD) patients and in animal models of PD. SN-infiltrated CD4+ T …

[HTML][HTML] Dopaminergic receptors on CD4+ T naive and memory lymphocytes correlate with motor impairment in patients with Parkinson's disease

N Kustrimovic, E Rasini, M Legnaro, R Bombelli… - Scientific reports, 2016 - nature.com
Parkinson's disease (PD) is characterized by loss of dopaminergic neurons in substantia
nigra pars compacta, α-synuclein (α-syn)-rich intraneuronal inclusions (Lewy bodies), and …

Adrenergic and dopaminergic modulation of immunity in multiple sclerosis: teaching old drugs new tricks?

M Cosentino, F Marino - Journal of Neuroimmune Pharmacology, 2013 - Springer
Multiple sclerosis (MS) is an autoimmune disorder of the CNS characterized by
inflammation, demyelination and axonal loss. Classical evidence in experimental allergic …

[HTML][HTML] Autoimmune epilepsy-novel multidisciplinary analysis, discoveries and insights

M Levite, H Goldberg - Frontiers in Immunology, 2022 - frontiersin.org
Epilepsy affects~ 50 million people. In~ 30% of patients the etiology is unknown, and~ 30%
are unresponsive to anti-epileptic drugs. Intractable epilepsy often leads to multiple seizures …

Dopamine, T cells and multiple sclerosis (MS)

M Levite, F Marino, M Cosentino - Journal of Neural Transmission, 2017 - Springer
Dopamine is a key neurotransmitter that induces critical effects in the nervous system and in
many peripheral organs, via 5 dopamine receptors (DRs): D1R–D5R. Dopamine also …

Expression of dopaminergic receptors on human CD4+ T lymphocytes: flow cytometric analysis of naive and memory subsets and relevance for the neuroimmunology …

N Kustrimovic, E Rasini, M Legnaro, F Marino… - Journal of Neuroimmune …, 2014 - Springer
Dopamine (DA) is a crucial transmitter in the neuroimmune network, where it contributes to
the nervous system-immune system interplay as well as in the communication among …

Targeting the dopamine D3 receptor: an overview of drug design strategies

A Cortes, E Moreno, M Rodriguez-Ruiz… - Expert opinion on …, 2016 - Taylor & Francis
Introduction: Dopamine is a neurotransmitter widely distributed in both the periphery and the
central nervous system (CNS). Its physiological effects are mediated by five closely related G …

A short social interaction between adult and old mice improves the homeostatic systems and increases healthy longevity

E Díaz-del Cerro, N Ceprián, J Félix… - Experimental …, 2022 - Elsevier
The aging process can be influenced by environmental factors, such as the social
environment. The continuous cohabitation of the chronologically old mice with adult animals …