Endogenous and exogenous neurotoxins are important factors leading to
neurodegenerative diseases. In the 1980s, the discovery that 1-methyl-4-phenyl-1, 2, 3, 6 …

Mitochondrial dysfunction is one of the crucial factors involved in PD's pathogenicity, which
emerges from a combination of genetic and environmental factors. These factors cause …

Malaria caused by Plasmodium affects millions people worldwide. Plasmodium consumes
hemoglobin during its intraerythrocytic stage leaving toxic heme. Parasite detoxifies free …

β-Carbolines are naturally occurring bioactive alkaloids found in foods and in vivo. This
research reports the identification, characterization, mechanism of formation, and …

β-Carbolines (βCs) are naturally occurring bioactive alkaloids, whereas α-dicarbonyl
compounds are reactive substances generated in foods and in vivo. In this work, l …

Monoamine oxidase (MAO) catalyzes the oxidative deamination of amines and
neurotransmitters and is involved in mood disorders, depression, oxidative stress, and …

Peganum harmala L. is a medicinal plant from the Mediterranean region and Asia currently
used for recreative psychoactive purposes (Ayahuasca analogue), and increasingly …

Monoamine oxidase (MAO) oxidizes neurotransmitters and xenobiotic amines, including
vasopressor and neurotoxic amines such as the MPTP neurotoxin. Its inhibitors are useful as …

Monoamine oxidase (MAO) enzymes catalyze the oxidative deamination of biogenic amines
and neurotransmitters and produce ammonia, aldehydes, and hydrogen peroxide which is …

β-Carbolines are naturally occurring bioactive alkaloids. In this work, carbohydrate-derived β-
carbolines (βCs), 1-(1, 3, 4, 5-tetrahydroxypent-1-yl)-β-carboline isomers (1a/b), 1-(1, 4, 5 …