This article provides an overview of the history of substance use and misuse and chronicles
the long shared history humans have had with psychoactive substances, including alcohol …

Acreditamos que o conhecimento é um bem público e comum. Por essa razão, os livros de
CLACSO estão disponíveis em acesso livre e gratuito. Se você quer comprar exemplares …

Simple Summary Alcohol consumption is linked to 26.4% of all lip and oral cavity cancer
cases worldwide. Despite this clear causal relationship, the exact molecular mechanisms by …

Humans have a long evolutionary relationship with ethanol, pre-dating anthropogenic
sources, and possess unusually efficient ethanol metabolism, through a mutation that …

The available data leaves no doubt that compulsive overworking is a genuine problem
related to significant harm. Thus far, most cases were recognized in relation to the official …

Background The medial prefrontal cortex (mPFC) inhibits impulsive and compulsive
behaviors that characterize drug abuse and dependence. Acamprosate is the leading …

Alcohol's effects on reactivity to stressors depend on the nature of the stressor and the
reactivity being assessed. Research that identifies characteristics of stressors that modulate …

Excessive alcohol consumption is the cause of several diseases and thus is of a major
concern for society. Worldwide alcohol consumption has increased by many folds over the …

We review the diagnostic criteria and core defining characteristics of the alcohol use
disorder (AUD) phenotype and briefly characterize the epidemiology of alcohol use …

As part of the special issue of Development and Psychopathology honoring the remarkable
contributions of Dr Dante Cicchetti, the current paper attempts to describe the recent …