Abstract The American Society of Regional Anesthesia and Pain Medicine (ASRA) 2012
survey of meeting attendees showed that existing ASRA anticoagulation guidelines for …

Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) of the phenylacetic acid class
with anti-inflammatory, analgesic, and antipyretic properties. Contrary to the action of many …

Non-steroidal anti-inflammatory drugs (NSAIDs), which act via inhibition of the
cyclooxygenase (COX) isozymes, were discovered more than 100 years ago. They remain a …

Platelets are small anucleate cell fragments that circulate in blood playing crucial role in
managing vascular integrity and regulating hemostasis. Platelets are also involved in the …

Background Pre-clinical models demonstrate that platelet activation is involved in the spread
of malignancy. Ongoing clinical trials are assessing whether aspirin, which inhibits platelet …

Arachidonic acid is one of the most abundant and ubiquitous ω-6 polyunsaturated fatty acid,
present in esterified form in the membrane phospholipids of all mammalian cells and …

Nonsteroidal antiinflammatory drugs (NSAIDs) are widely used to treat arthritis, menstrual
pain, and headache. Although they are effective, their long-term use is limited by …

Because metastasis is associated with the majority of cancer-related deaths, its prevention is
a clinical aspiration. Prostanoids are a large family of bioactive lipids derived from the …

This review considers the role of low-dose aspirin for the prevention of atherothrombosis,
discussing the molecular mechanism of action of aspirin as well as clinical and …

The past 10 years have witnessed major changes in our understanding of the
pathophysiologic mechanisms underlying vascular occlusion1, 2 and considerable progress …