The gut microbiota (microbiome) in cardiovascular disease and its therapeutic regulation

MM Rahman, F Islam, MH -Or-Rashid… - Frontiers in cellular …, 2022 - frontiersin.org
In the last two decades, considerable interest has been shown in understanding the
development of the gut microbiota and its internal and external effects on the intestine, as …

Gut microbiota in hypertension and atherosclerosis: a review

BJH Verhaar, A Prodan, M Nieuwdorp, M Muller - Nutrients, 2020 - mdpi.com
Gut microbiota and its metabolites such as short chain fatty acids (SCFA),
lipopolysaccharides (LPS), and trimethylamine-N-oxide (TMAO) impact cardiovascular …

Gut microbiota and their metabolites in stroke: a double-edged sword

A Peh, JA O'Donnell, BRS Broughton, FZ Marques - Stroke, 2022 - Am Heart Assoc
Besides damaging the brain, stroke causes systemic changes, including to the
gastrointestinal system. A growing body of evidence supports the role of the gut and its …

Gut microbiota in cardiovascular health and disease

WHW Tang, T Kitai, SL Hazen - Circulation research, 2017 - Am Heart Assoc
Significant interest in recent years has focused on gut microbiota–host interaction because
accumulating evidence has revealed that intestinal microbiota play an important role in …

[HTML][HTML] Gut microbiota dependent trimethylamine N-oxide aggravates angiotensin II–induced hypertension

S Jiang, Y Shui, Y Cui, C Tang, X Wang, X Qiu, W Hu… - Redox biology, 2021 - Elsevier
Gut microbiota produce Trimethylamine N-oxide (TMAO) by metabolizing dietary
phosphatidylcholine, choline, l-carnitine and betaine. TMAO is implicated in the …

Recent advances in modulation of cardiovascular diseases by the gut microbiota

SK Masenga, B Hamooya, J Hangoma… - Journal of Human …, 2022 - nature.com
The gut microbiota has recently gained attention due to its association with cardiovascular
health, cancers, gastrointestinal disorders, and non-communicable diseases. One critical …

Alterations of the gut microbiome in hypertension

Q Yan, Y Gu, X Li, W Yang, L Jia, C Chen… - Frontiers in cellular …, 2017 - frontiersin.org
Introduction: Human gut microbiota is believed to be directly or indirectly involved in
cardiovascular diseases and hypertension. However, the identification and functional status …

Crosstalk between gut microbiota and host immunity: impact on inflammation and immunotherapy

C Campbell, MR Kandalgaonkar, RM Golonka… - Biomedicines, 2023 - mdpi.com
Gut microbes and their metabolites are actively involved in the development and regulation
of host immunity, which can influence disease susceptibility. Herein, we review the most …

Beyond gut feelings: how the gut microbiota regulates blood pressure

FZ Marques, CR Mackay, DM Kaye - Nature Reviews Cardiology, 2018 - nature.com
Hypertension is the leading risk factor for heart disease and stroke, and is estimated to
cause 9.4 million deaths globally every year. The pathogenesis of hypertension is complex …

The gut microbiome in hypertension: recent advances and future perspectives

EG Avery, H Bartolomaeus, A Maifeld, L Marko… - Circulation …, 2021 - Am Heart Assoc
The pathogenesis of hypertension is known to involve a diverse range of contributing factors
including genetic, environmental, hormonal, hemodynamic and inflammatory forces, to …