More than a century ago, August Weissman defined a distinction between the germline
(responsible for propagating heritable information from generation to generation) and the …

Endothelial progenitor cells (EPCs), which are a type of stem cell, have been found to have
strong angiogenic and tissue repair capabilities. Extracellular vesicles (EVs) contain many …

Uterine environment is tightly and finely regulated via various signaling pathways mediated
through endocrine, exocrine, autocrine, juxtacrine, and paracrine mechanisms. In utero …

Embryo/fetal nutrition and the environment in the reproductive tract influence the subsequent
risk of developing adult diseases and disorders, as formulated in the Barker hypothesis …

Background Fetal cell-derived exosomes (extracellular vesicles, 40–160 nm) are
communication channels that can signal parturition by inducing inflammatory changes in …

During the process of sex determination, a germ-cell-containing undifferentiated gonad is
converted into either a male or a female reproductive organ. Both the composition of sex …

In this review we discuss the beneficial effects of amino acid transport and metabolism on
pre-and peri-implantation embryo development, and we consider how disturbances in these …

Extracellular vesicles (EVs) are gaining increasing amounts of attention due to their potential
use in diagnostics and therapy, but the poor reproducibility of the studies that have been …

Extracellular vesicles are nanoscale vesicles that transport signals between cells, mediating
both physiological and pathological processes. EVs facilitate conserved intercellular …

STUDY QUESTION Do extracellular vesicles (EVs) from human Fallopian tubes exert an
influence on early embryo development in vitro? SUMMARY ANSWER Human Fallopian …