Strategies for improving bioavailability, bioactivity, and physical-chemical behavior of curcumin

LZ Racz, CP Racz, LC Pop, G Tomoaia, A Mocanu… - Molecules, 2022 - mdpi.com
Curcumin (CCM) is one of the most frequently explored plant compounds with various
biological actions such as antibacterial, antiviral, antifungal, antineoplastic, and …

The relevance of targeting treatment to small airways in asthma and COPD

P Santus, D Radovanovic, M Pecchiari… - Respiratory …, 2020 - rc.rcjournal.com
COPD and asthma have different risk factors and pathogenesis, but they share a
pathophysiologic hallmark characterized by small airways disease. Although difficult to …

Molecular insight into binding behavior of polyphenol (rutin) with beta lactoglobulin: Spectroscopic, molecular docking and MD simulation studies

NA Al-Shabib, JM Khan, A Malik, MA Alsenaidy… - Journal of Molecular …, 2018 - Elsevier
The interaction of natural polyphenolic compounds (rutin) with β-lactoglobulin (BLG) was
carried out by using several optical spectroscopic (UV–visible spectroscopy, fluorescence …

On the purported “backbone fluorescence” in protein three-dimensional fluorescence spectra

A Bortolotti, YH Wong, SS Korsholm, NHB Bahring… - Rsc Advances, 2016 - pubs.rsc.org
In this study, several proteins (albumin, lysozyme, insulin) and model compounds (Trp, Tyr,
homopolypeptides) were used to demonstrate the origin of the fluorescence observed upon …

Fluorescence spectroscopic and molecular docking studies of the binding interaction between the new anaplastic lymphoma kinase inhibitor crizotinib and bovine …

AS Abdelhameed, AM Alanazi, AH Bakheit… - … Acta Part A: Molecular …, 2017 - Elsevier
Binding of the recently introduced anti-cancer drug, crizotinib (CRB) with the bovine serum
albumin (BSA) was comprehensively studied with the aid of fluorescence and UV–Vis …

Phase separation, aggregation, and complexation of triton-X100 and bovine serum albumin mixture: A combined cloud point and UV–visible spectroscopic …

HA Bhuiyan, JM Khan, D Kumar, MK Banjare… - International Journal of …, 2024 - Elsevier
Phase separation and aggregation behaviour of triton X-100 (TX-100) and bovine serum
albumin (BSA) mixture were investigated using cloud point and UV–visible spectroscopic …

Investigation of interactions between zein and natamycin by fluorescence spectroscopy and molecular dynamics simulation

X Wu, X Zhao, Z Deng, X Liang, S Fang - Journal of Molecular Liquids, 2021 - Elsevier
Zein nanoparticles have been demonstrated as an efficient nanocarrier for natamycin to
improve its solubility and stability. This study investigated the molecular-level interactions …

Effects of Heme site (FA1) ligands bilirubin, biliverdin, hemin, and methyl orange on the albumin binding of site I marker warfarin: complex allosteric interactions

B Lemli, Z Lomozová, T Huber, A Lukács… - International Journal of …, 2022 - mdpi.com
Human serum albumin (HSA) is the most abundant plasma protein in circulation. The three
most important drug-binding sites on HSA are Sudlow's Site I (subdomain IIA), Sudlow's Site …

A hybrid nanoparticle-protein hydrogel system for prolonged local anesthesia

W Choi, G Aizik, CA Ostertag-Hill, DS Kohane - Biomaterials, 2024 - Elsevier
Local anesthetics are effective in relieving pain, but their duration of action is short.
Therefore, the development of injectable sustained release systems to prolong the effect of …

Intrinsically fluorescent anti-cancer drugs

ML Kabir, F Wang, AHA Clayton - Biology, 2022 - mdpi.com
Simple Summary Cancer is one of the biggest causes of death world-wide. The
development of anti-cancer drugs is important in combatting this disease. As good as these …