Neuroactive steroids refer to steroids that are capable of regulating neuronal activities.
Neuroactive steroids, synthesized either de novo in the nervous tissue or in the peripheral …

A vast number of marketed drugs act on G protein‐coupled receptors (GPCRs), the most
successful category of drug targets to date. These drugs usually possess high target affinity …

Substance dependence is characterized by compulsive drug-taking despite negative
consequences. Animal research suggests an underlying imbalance between goal-directed …

Social interaction deficits and restricted repetitive behaviors and interests that characterize
autism spectrum disorders (ASDs) may both reflect aberrant functioning of brain reward …

In detoxified alcohol‐dependent patients, alcohol‐related stimuli can promote relapse.
However, to date, the mechanisms by which contextual stimuli promote relapse have not …

Several psychiatric disorders are associated with white matter defects, suggesting that
oligodendrocyte (OL) abnormalities underlie some aspects of these diseases. Neuregulin 1 …

This article investigates the functional connectivity patterns of the nucleus accumbens
(NAcc) in 18 healthy participants using a resting state functional connectivity (rsFC) protocol …

To represent value for learning and decision making, the brain must encode information
about both the motivational relevance and affective valence of anticipated outcomes. The …

A new rapid, convenient and sensitive electrochemical method based on a gold
nanoparticles modified ITO (Au/ITO) electrode is described for the detection of dopamine …

Background Dopamine is a catecholamine that is used as a neurotransmitter both in the
periphery and in the central nervous system. Dysfunction in various dopaminergic systems is …