Pharmacokinetics, pharmacodynamics and drug–drug interactions of new anti-migraine drugs—Lasmiditan, gepants, and calcitonin-gene-related peptide (CGRP) …
D Szkutnik-Fiedler - Pharmaceutics, 2020 - mdpi.com
In the last few years, there have been significant advances in migraine management and
prevention. Lasmiditan, ubrogepant, rimegepant and monoclonal antibodies (erenumab …
prevention. Lasmiditan, ubrogepant, rimegepant and monoclonal antibodies (erenumab …
Calcitonin gene-related peptide (CGRP)-targeted monoclonal antibodies and antagonists in migraine: current evidence and rationale
Calcitonin gene-related peptide (CGRP), a 37 amino-acid neuropeptide found mostly in
peptidergic sensory C-fibers, has been suggested to be implicated in the pathogenesis of …
peptidergic sensory C-fibers, has been suggested to be implicated in the pathogenesis of …
[HTML][HTML] Lower Urinary Tract Symptoms in Depression: A Review
DJ Anderson, A Aucoin, CR Toups… - Health Psychology …, 2023 - ncbi.nlm.nih.gov
Abstract Lower Urinary Tract Symptoms (LUTS) are frequently present in the general
population as patients age with approximately a third of individuals experiencing LUTS …
population as patients age with approximately a third of individuals experiencing LUTS …
Monthly migraine days, tablet utilization, and quality of life associated with Rimegepant–post hoc results from an open label safety study (BHV3000–201)
Background The objective of this study was to describe patterns in monthly migraine days
(MMD) and tablet utilization, and to estimate health-related quality of life (HRQoL) measures …
(MMD) and tablet utilization, and to estimate health-related quality of life (HRQoL) measures …
JP3, an antiangiogenic peptide, inhibits growth and metastasis of gastric cancer through TRIM25/SP1/MMP2 axis
JJ Chen, YL Ren, CJ Shu, Y Zhang, MJ Chen… - Journal of Experimental …, 2020 - Springer
Background Gastric cancer (GC) is the most prevalent gastrointestinal tumor with an
unfavorable clinical prognosis. GC patients are largely threatened owing to metastasis and …
unfavorable clinical prognosis. GC patients are largely threatened owing to metastasis and …
Outpatient Approach to resistant and refractory migraine in children and adolescents: a Narrative Review
A Marshall, R Lindsay, MA Clementi… - Current Neurology and …, 2022 - Springer
Abstract Purpose of Review Migraine is one of the top reasons for consulting a pediatric
neurologist. Although the majority of children and adolescents who receive evidence-based …
neurologist. Although the majority of children and adolescents who receive evidence-based …
A systematic review with expert opinion on the role of gepants for the preventive and abortive treatment of migraine
Introduction Gepants are small molecules targeting the calcitonin gene-related peptide
(CGRP) that have been recently introduced and are under additional clinical development …
(CGRP) that have been recently introduced and are under additional clinical development …
Comparative efficacy of oral calcitonin-gene–related peptide antagonists for the treatment of acute migraine: updated meta-analysis
Abstract Background and Objective The calcitonin gene-related peptide (CGRP) is a new
therapeutic target in migraine—a common disorder resulting in reduced quality of life. The …
therapeutic target in migraine—a common disorder resulting in reduced quality of life. The …
Evaluating rimegepant for the treatment of migraine
T de Vries, L Al-Hassany… - Expert opinion on …, 2021 - Taylor & Francis
Introduction Calcitonin gene-related peptide (CGRP) is a vasodilatory neuropeptide
involved in the pathophysiology of migraine, a highly disabling neurovascular disorder …
involved in the pathophysiology of migraine, a highly disabling neurovascular disorder …
[HTML][HTML] Rimegepant for the treatment of migraine
Migraine is a common form of primary headache, affecting up to 1 in every 6 Americans. The
pathophysiology is an intricate interplay of genetic factors and environmental influence and …
pathophysiology is an intricate interplay of genetic factors and environmental influence and …