[HTML][HTML] Plasmin and plasminogen system in the tumor microenvironment: implications for cancer diagnosis, prognosis, and therapy
AG Bharadwaj, RW Holloway, VA Miller, DM Waisman - Cancers, 2021 - mdpi.com
Simple Summary In this review, we present a detailed discussion of how the plasminogen-
activation system is utilized by tumor cells in their unrelenting attack on the tissues …
activation system is utilized by tumor cells in their unrelenting attack on the tissues …
Fibrinogen and fibrin: synthesis, structure, and function in health and disease
AS Wolberg - Journal of Thrombosis and Haemostasis, 2023 - Elsevier
Fibrinogen is an extraordinary molecule by any estimation. It is large, structurally intricate,
and circulates at high concentrations. Its biological end product, insoluble fibrin (ogen) or …
and circulates at high concentrations. Its biological end product, insoluble fibrin (ogen) or …
[HTML][HTML] TCF7L2 promotes anoikis resistance and metastasis of gastric cancer by transcriptionally activating PLAUR
T Zhang, B Wang, F Su, B Gu, L Xiang… - … Journal of Biological …, 2022 - ncbi.nlm.nih.gov
Gastric cancer (GC) is the most common gastrointestinal malignant tumor, and distant
metastasis is a critical factor in the prognosis of patients with GC. Understanding the …
metastasis is a critical factor in the prognosis of patients with GC. Understanding the …
Endothelial regulation of drug transport in a 3D vascularized tumor model
Drug discovery and efficacy in cancer treatments are limited by the inability of pre‐clinical
models to predict successful outcomes in humans. Limitations remain partly due to their lack …
models to predict successful outcomes in humans. Limitations remain partly due to their lack …
[HTML][HTML] Gold nanoparticles based optical biosensors for cancer biomarker proteins: a review of the current practices
J Tai, S Fan, S Ding, L Ren - Frontiers in Bioengineering and …, 2022 - frontiersin.org
Cancer prognosis depends on the early detection of the disease. Gold nanoparticles
(AuNPs) have attracted much importance in biomedical research due to their distinctive …
(AuNPs) have attracted much importance in biomedical research due to their distinctive …
Enabling perfusion through multicellular tumor spheroids promoting lumenization in a vascularized cancer model
A tumor is composed of heterogeneous cell population, which is known as tumor stroma. In
particular, blood vessels have an indispensable role in the tumor microenvironment acting …
particular, blood vessels have an indispensable role in the tumor microenvironment acting …
The role of coagulome in the tumor immune microenvironment
The rising incidence and persistent thrombosis in multiple cancers including those that are
immunosuppressive highlight the need for understanding the tumor coagulome system and …
immunosuppressive highlight the need for understanding the tumor coagulome system and …
[HTML][HTML] Remodeling cancer stemness by collagen/fibronectin via the AKT and CDC42 signaling pathway crosstalk in glioma
C Zhong, B Tao, F Tang, X Yang, T Peng, J You… - Theranostics, 2021 - ncbi.nlm.nih.gov
Cancer development is a complex set of proliferative progression, which arises in most
cases via multistep pathways associated with various factors, including the tumor …
cases via multistep pathways associated with various factors, including the tumor …
Precise fibrin decomposition and tumor mechanics modulation with hydroxyethyl starch-based smart nanomedicine for enhanced antitumor efficacy
J Chen, Z Zhang, Y Li, H Zeng, Z Li, C Wang… - Journal of Materials …, 2022 - pubs.rsc.org
Chemotherapy is a conventional cancer treatment in clinical settings. Although numerous
nano drug delivery systems have been developed, the chemotherapeutic effect is greatly …
nano drug delivery systems have been developed, the chemotherapeutic effect is greatly …
Global coagulation assays in hypercoagulable states
HY Lim, G Donnan, H Nandurkar, P Ho - Journal of thrombosis and …, 2022 - Springer
Thrombosis is one of the major global causes of morbidity and mortality, and predicting the
risk of thrombotic and cardiovascular complications remains one of the key challenges in …
risk of thrombotic and cardiovascular complications remains one of the key challenges in …