Lipids are a complex and diverse group of molecules with crucial roles in many
physiological processes, as well as in the onset, progression, and maintenance of cancers …

Significance: Cholesterol is a type of lipid that plays a crucial role in building and
maintaining cell membranes, producing certain hormones, and aiding in digestion. The two …

Drug resistance is a serious challenge for platinum anticancer drugs. Platinum complexes
may get over the drug resistance via a distinct mechanism of action. Cholesterol is a key …

Hepatic cholesterol accumulation and hypercholesterolemia are implicated in hepatocellular
carcinoma (HCC). However, the therapeutic effects of cholesterol-lowering drugs on HCC …

Hepatocellular carcinoma (HCC) represents a leading cause of cancer-related deaths
globally. The rising incidence of metabolic syndrome and its hepatic manifestation …

Monascus-fermented red mold rice (RMR) has excellent physiological efficacy on lipid
metabolism and liver function. This study investigated the ameliorative effects of …

Hepatocellular carcinoma (HCC) is one of the most common malignant tumors with high
morbidity and mortality. Targeting abnormal cholesterol metabolism is a potential …

Cancer cells undergo drastic metabolic adaptions to cover increased bioenergetic needs,
contributing to resistance to therapies. This includes a higher demand for cholesterol, which …

The low-density-lipoprotein receptors represent a family of pleiotropic cell surface receptors
involved in lipid homeostasis, cell migration, proliferation and differentiation. The family …

Cholesterol is an essential component of cell membranes and helps to maintain their
structure and function. Abnormal cholesterol metabolism has been linked to the …