The green platform molecule gamma-valerolactone–ecotoxicity, biodegradability, solvent properties, and potential applications

F Kerkel, M Markiewicz, S Stolte, E Müller, W Kunz - Green Chemistry, 2021 - pubs.rsc.org
Since many decades, gamma-valerolactone (GVL) is known to be an excellent solvent,
which, today, can be made of sustainable materials. Although numerous publications praise …

Solvents derived from biomass and their potential as green solvents

L Lomba, E Zuriaga, B Giner - Current Opinion in Green and Sustainable …, 2019 - Elsevier
Highlights•Thanks to their renewable source, solvents from biomass are considered green
solvents.•Physical, chemical and (eco) toxicological properties should be analysed to …

Ethyl lactate and its aqueous solutions as sustainable media for organic synthesis

AV Dolzhenko - Sustainable chemistry and pharmacy, 2020 - Elsevier
Ethyl lactate is an amphiphilic bio-based solvent with beneficial safety characteristics and
ecotoxicity profile. The miscibility of ethyl lactate with water allows adjustments of the …

Solubility enhancement of caffeine and furosemide using deep eutectic solvents formed by choline chloride and xylitol, citric acid, sorbitol or glucose

L Lomba, A Polo, J Alejandre, N Martínez… - Journal of Drug Delivery …, 2023 - Elsevier
The low solubility of active pharmaceutical ingredients (APIs) in aqueous medium hinders
the formulation of drugs in liquid solvents. Several methodologies are used to improve their …

Ecotoxicological study of bio-based deep eutectic solvents formed by glycerol derivatives in two aquatic biomodels

MP Garralaga, L Lomba, A Leal-Duaso… - Green …, 2022 - pubs.rsc.org
The growing environmental impact of non-renewable solvents has generated an increasing
interest in the development of more sustainable alternatives. Among these options, deep …

Ecotoxicity interspecies study of ionic liquids based on phosphonium and ammonium cations

D Errazquin, A Mohamadou, L Dupont… - … Science and Pollution …, 2021 - Springer
This work studies the effects of different bromide-based ionic liquids, with phosphonium and
ammonium cations, towards several environmental biomodels: Daphnia magna, Allivibrio …

QSAR study for predicting the ecotoxicity of NADES towards Aliivibrio fischeri. Exploring the use of mixing rules

B Giner, C Lafuente, D Lapeña, D Errazquin… - Ecotoxicology and …, 2020 - Elsevier
Abstract (Eco) toxicological information of natural deep eutectic solvents (NADES) is scarce,
and thus, quantitative structure activity relationship (QSAR) models are an important tool for …

[HTML][HTML] Kinetics of alkyl lactate formation from the alcoholysis of poly (lactic acid)

FM Lamberti, LA Román-Ramírez, P Mckeown… - Processes, 2020 - mdpi.com
Alkyl lactates are green solvents that are successfully employed in several industries such
as pharmaceutical, food and agricultural. They are considered prospective renewable …

Evaluation of the toxicity profiles of three families of solvents from biomass: levulinate, lactate and furfural derivatives

E Zuriaga, L Lomba, CB García, MS Valero - Green Chemistry, 2023 - pubs.rsc.org
Nowadays, the scientific community is looking for and developing new solvents, called
green solvents, which, due to their physicochemical properties and their origin, can replace …

Deep eutectic solvents based on sugars for oral applications

L Lomba, A Polo, Á Werner, C Lafuente… - European Journal of …, 2023 - Elsevier
Solubility is a critical parameter in drug formulation to achieve the desired therapeutical
concentration. Most drugs are weak acids or bases and, therefore, exhibit low solubility and …