GATA transcription factors in development and disease

M Tremblay, O Sanchez-Ferras, M Bouchard - Development, 2018 - journals.biologists.com
The GATA family of transcription factors is of crucial importance during embryonic
development, playing complex and widespread roles in cell fate decisions and tissue …

PDGF-BB exhibited therapeutic effects on rat model of bisphosphonate-related osteonecrosis of the jaw by enhancing angiogenesis and osteogenesis

S Gao, R Lin, S Huang, Y Liang, X Li, S Zhang… - Bone, 2021 - Elsevier
The mechanism and effective treatment of bisphosphonate-related osteonecrosis of the jaw
(BRONJ) are still uncertain. Our previous study revealed that zoledronate (ZOL) …

The role of LncRNAs and CircRNAs in osteoporosis: a focus on osteogenesis and osteoclastogenesis signaling pathways

SM Ismail, MA Abd-Elmawla, MI Shabayek… - Future Journal of …, 2024 - Springer
Background Osteoporosis is a crucial health concern interconnected with physical
disabilities as well as financial burdens. It arises from an imbalance between osteoblasts …

Osteocytes promote osteoclastogenesis via autophagy-mediated RANKL secretion under mechanical compressive force

W Li, J Zhao, W Sun, H Wang, Y Pan, L Wang… - Archives of Biochemistry …, 2020 - Elsevier
Osteocytes sense extracellular mechanical stimuli and transduce them into biochemical
signals to regulate bone remodeling. The function is also evidenced in orthodontic tooth …

Dopamine D1 receptor-mediated activation of the ERK signaling pathway is involved in the osteogenic differentiation of bone mesenchymal stem cells

CX Wang, XY Ge, MY Wang, T Ma, Y Zhang… - Stem Cell Research & …, 2020 - Springer
Background Osteogenic differentiation of bone mesenchymal stem cells (BMSCs) is
regulated by numerous signaling pathways. Dopamine (DA), a neurotransmitter, has …

Polysaccharide-protein complex-decorated selenium nanosystem as an efficient bone-formation therapeutic

K Wing-HináKwok - Journal of Materials Chemistry B, 2018 - pubs.rsc.org
Polysaccharide-protein complex-coated selenium nanoparticles (PTR-SeNPs) system has
been rationally designed and identified as a potent bone-formation therapeutic to …

Discoidin domain receptor 1 regulates runx2 during osteogenesis of osteoblasts and promotes bone ossification via phosphorylation of p38

LY Chou, CH Chen, SC Chuang, TL Cheng… - International journal of …, 2020 - mdpi.com
Discoidin domain receptor 1 (Drd1) is a collagen-binding membrane protein, but its role in
osteoblasts during osteogenesis remains undefined. We generated inducible osteoblast …

CTHRC1 promotes osteogenic differentiation of periodontal ligament stem cells by regulating TAZ

C Wang, W Gu, B Sun, Y Zhang, Y Ji, X Xu… - Journal of Molecular …, 2017 - Springer
Collagen triple helix repeat containing 1 (CTHRC1) is associated with bone metabolism.
Alveolar bone has an ability to rapidly remodel itself to adapt its biomechanical environment …

Hesperidin promotes differentiation of alveolar osteoblasts via Wnt/β-Catenin signaling pathway

W Hong, W Zhang - Journal of Receptors and Signal Transduction, 2020 - Taylor & Francis
Alveolar bone has a high plasticity. The health of alveolar bones directly determines the
success of oral implant surgery, and the health and functions of oral and maxillofacial …

[HTML][HTML] GATA4-activated lncRNA MALAT1 promotes osteogenic differentiation through inhibiting NEDD4-mediated RUNX1 degradation

X Huang, S Jie, W Li, C Liu - Cell Death Discovery, 2023 - nature.com
Postmenopausal osteoporosis (PMOP) brings a lot of inconvenience to patients and serious
economic burden to society. The osteogenic differentiation of bone marrow mesenchymal …