A mini-review of the NADPH oxidases in vascular dementia: correlation with NOXs and risk factors for VaD

DH Choi, J Lee - International Journal of Molecular Sciences, 2017 - mdpi.com
Oxidative stress (OS) is one of the factors that cause dementia conditions such as
Alzheimer's disease and vascular dementia (VaD). In the pathogenesis of VaD, OS is …

Behavioral and biochemical investigations to explore the efficacy of quercetin and folacin in experimental diabetes induced vascular endothelium dysfunction and …

P Sharma, K Aggarwal, R Awasthi… - Journal of Basic and …, 2023 - degruyter.com
Abstract Objectives Vascular dementia (VaD), being strongly associated with metabolic
conditions is a major health concern around the world. Diabetes is a major risk factor for the …

Experimental hypertension induced vascular dementia: pharmacological, biochemical and behavioral recuperation by angiotensin receptor blocker and …

B Sharma, N Singh - Pharmacology Biochemistry and Behavior, 2012 - Elsevier
Involvement of vascular pathology has been suggested in hypertension as well as vascular
dementia (VaD), which also have a very high degree of co-occurrence in ageing population …

Etanercept improves cognitive performance and increases eNOS and BDNF expression during experimental vascular dementia in streptozotocin-induced diabetes

T Utkan, Y Yazir, A Karson… - Current neurovascular …, 2015 - ingentaconnect.com
Diabetes mellitus (DM) is related to an increase in the incidence of vascular dementia.
Inflammation is an important cause of endothelial dysfunction and cognitive deficits. The anti …

Melatonin receptor and KATP channel modulation in experimental vascular dementia

P Singh, S Gupta, B Sharma - Physiology & Behavior, 2015 - Elsevier
Cerebrovascular and cardiovascular diseases are stated as important risk factors of vascular
dementia (VaD) and other cognitive disorders. In the central nervous system, melatonin (MT …

Pharmacological modulation of I1-imidazoline and α2-adrenoceptors in sub acute brain ischemia induced vascular dementia

S Gupta, B Sharma - European Journal of Pharmacology, 2014 - Elsevier
Sub-acute brain ischemia is a risk factor for the development of vascular dementia (VaD).
Sub-acute brain ischemia induced VaD, participates in a negative role in impaired cognition …

Tadalafil ameliorates memory deficits, oxidative stress, endothelial dysfunction and neuropathological changes in rat model of hyperhomocysteinemia induced …

P Bhatia, N Singh - International Journal of Neuroscience, 2022 - Taylor & Francis
Aim The present study investigates the potential of Tadalafil, a phosphodiesterase-5
inhibitor, in a rat model of hyperhomocysteinemia induced vascular dementia. Methods …

Berberine suppresses the ectopic expression of miR-133a in endothelial cells to improve vascular dementia in diabetic rats

S Yin, W Bai, P Li, X Jian, T Shan, Z Tang… - Clinical and …, 2019 - Taylor & Francis
Objective: Vascular dementia is the second leading cause of dementia, which is strongly
associated with diabetes. Ectopic expression of miR-133a in endothelial cells is involved in …

Efficacy of Cilostazol a selective phosphodiesterase-3 inhibitor in rat model of Streptozotocin diabetes induced vascular dementia

A Kumar, A Kumar, AS Jaggi, N Singh - Pharmacology Biochemistry and …, 2015 - Elsevier
The present study has been designed to investigate the potential of Cilostazol a
phosphodiesterase-3 (PDE-3) inhibitor in diabetes-induced vascular dementia (Vad) …

[HTML][HTML] Efficacy of ulinastatin and sulforaphane alone or in combination in rat model of streptozotocin diabetes induced vascular dementia

P Sharma, P Kaushik, S Jain, BM Sharma… - Clinical …, 2021 - ncbi.nlm.nih.gov
Objective Vascular Dementia (VaD), is associated with metabolic conditions. Diabetes is a
major risk factor for the development of VaD. This study investigates the efficacy of …