Updated recommendations regarding the management of older patients with breast cancer: a joint paper from the European Society of Breast Cancer Specialists …

L Biganzoli, NML Battisti, H Wildiers… - The Lancet …, 2021 - thelancet.com
Breast cancer is increasingly prevalent in older adults and is a substantial part of routine
oncology practice. However, management of breast cancer in this population is challenging …

Ovarian cancer in the older patient: where are we now? What to do next?

F Rousseau, F Ranchon, C Bardin… - Therapeutic …, 2023 - journals.sagepub.com
In recent years, major advances have been made toward the individualization of epithelial
ovarian cancer care, leading to an overall improvement of patient outcomes. However, real …

[HTML][HTML] Pathogenesis and potential therapeutic targets for triple-negative breast cancer

CJ Li, YDT Tzeng, YH Chiu, HY Lin, MF Hou, PY Chu - Cancers, 2021 - mdpi.com
Simple Summary Breast cancer emergencies have become a rapidly evolving field in
medicine during the last ten years. Carcinogenesis is a multiparametric process that …

Efficacy and safety of PARP inhibitors in elderly patients with advanced ovarian cancer: a systematic review and meta-analysis

BA Maiorano, MFP Maiorano, D Lorusso… - International Journal of …, 2022 - ijgc.bmj.com
Background Poly-(ADP-ribose)-polymerase (PARP) inhibitors have shown to be effective as
maintenance treatment in patients with advanced ovarian cancer. Although most ovarian …

[HTML][HTML] Efficacy and safety of maintenance olaparib and bevacizumab in ovarian cancer patients aged≥ 65 years from the PAOLA-1/ENGOT-ov25 trial

R Sabatier, F Rousseau, F Joly, C Cropet… - European Journal of …, 2023 - Elsevier
Abstract Background The phase III PAOLA-1/ENGOT-ov25 study (NCT02477644) showed
that addition of olaparib to bevacizumab maintenance improved progression-free survival …

[HTML][HTML] Personalising therapy for early-stage oestrogen receptor-positive breast cancer in older women

N Carleton, A Nasrazadani, K Gade… - The Lancet Healthy …, 2022 - thelancet.com
Age is one of the most important risk factors for the development of breast cancer. Nearly a
third of all breast cancer cases occur in older women (aged≥ 70 years), with most cases …

[HTML][HTML] Oncological treatment-related fatigue in oncogeriatrics: a scoping review

L André, G Antherieu, A Boinet, J Bret, T Gilbert… - Cancers, 2022 - mdpi.com
Simple Summary Fatigue in older patients has multiple etiologies, as this symptom may be
cancer-related, treatment-related, age-related, or part of frailty syndrome. Physicians need to …

[HTML][HTML] The effect of age on efficacy, safety and patient-centered outcomes with rucaparib: a post hoc exploratory analysis of ARIEL3, a phase 3, randomized …

N Colombo, AM Oza, D Lorusso, C Aghajanian… - Gynecologic …, 2020 - Elsevier
Background In the phase 3 trial ARIEL3, maintenance treatment with the poly (ADP-ribose)
polymerase (PARP) inhibitor rucaparib provided clinical benefit versus placebo for patients …

SIOG guidelines-essential for good clinical practice in geriatric oncology

R Dubianski, TM Wildes… - Journal of geriatric …, 2019 - geriatriconcology.net
As a result of aging of the population, the number of older patients with cancer is growing
worldwide. Optimal approach and treatment strategies for older cancer patients can …

[HTML][HTML] Multi-disciplinary care planning of ovarian cancer in older patients: general statement—a position paper from SOFOG-GINECO-FRANCOGYN-SFPO

L Bengrine, N Bakrin, F Rousseau, V Lavoué… - Cancers, 2022 - mdpi.com
Simple Summary This position paper aims to provide practitioners a proposal for
multidisciplinary care planning for older patients with ovarian cancer from the time of …