Mechanisms of action of disease-modifying agents and brain volume changes in multiple sclerosis

R Zivadinov, AT Reder, M Filippi, A Minagar, O Stuve… - Neurology, 2008 - AAN Enterprises
Disease-modifying agents (DMAs), including interferon beta (IFNβ) and glatiramer acetate
(GA), are the mainstays of long-term treatment of multiple sclerosis (MS). Other potent anti …

Brain atrophy assessment in multiple sclerosis: importance and limitations

A Giorgio, M Battaglini, SM Smith… - Neuroimaging Clinics of …, 2008 - Elsevier
The use of MR imaging–derived methods to provide sensitive and reproducible
assessments of brain volume (eg, to estimate atrophy) has increased the interest in this …

Characterizing iron deposition in multiple sclerosis lesions using susceptibility weighted imaging

EM Haacke, M Makki, Y Ge… - Journal of Magnetic …, 2009 - Wiley Online Library
Purpose To investigate whether the variable forms of putative iron deposition seen with
susceptibility weighted imaging (SWI) will lead to a set of multiple sclerosis (MS) lesion …

[图书][B] Clinical neurology

RP Simon, MJ Aminoff, DA Greenberg - 2009 - ndl.ethernet.edu.et
The warm and generous acceptance of earlier editions of this book and the advances that
have occurred in the neurosciences in the last few years have prompted the preparation of …

[HTML][HTML] Effects of aging on , , and QSM MRI values in the subcortex

MC Keuken, PL Bazin, K Backhouse… - Brain Structure and …, 2017 - Springer
The aging brain undergoes several anatomical changes that can be measured with
Magnetic Resonance Imaging (MRI). Early studies using lower field strengths have …

Magnetic resonance imaging characteristics of children and adults with paediatric-onset multiple sclerosis

EA Yeh, B Weinstock-Guttman, M Ramanathan… - Brain, 2009 - academic.oup.com
The purpose of this study was to compare the clinical and quantitative magnetic resonance
imaging metrics of paediatric-onset multiple sclerosis to adult-onset multiple sclerosis. It was …

Placebo-controlled trial of oral laquinimod in multiple sclerosis: MRI evidence of an effect on brain tissue damage

M Filippi, MA Rocca, E Pagani, N De Stefano… - Journal of Neurology …, 2014 - jnnp.bmj.com
Objective In A ssessment of Ora LL aquinimod in Pr E venting Pro GR ession in Multiple
Scler O sis (ALLEGRO), a phase III study in relapsing-remitting multiple sclerosis (RRMS) …

Relationship of optic nerve and brain conventional and non-conventional MRI measures and retinal nerve fiber layer thickness, as assessed by OCT and GDx: a pilot …

EM Frohman, MG Dwyer, T Frohman, JL Cox… - Journal of the …, 2009 - Elsevier
BACKGROUND: Measurement of retinal nerve fiber layer (RNFL) thickness in multiple
sclerosis (MS) is gaining increasing attention. OBJECTIVES: To explore the relationship …

Atrophied brain T2 lesion volume at MRI is associated with disability progression and conversion to secondary progressive multiple sclerosis

AV Genovese, J Hagemeier, N Bergsland… - Radiology, 2019 - pubs.rsna.org
Background Atrophied T2 lesion volume at MRI is an imaging measure that reflects the
replacement of T2 lesions by cerebrospinal fluid spaces in patients with multiple sclerosis …

[HTML][HTML] Improving the characterization of radiologically isolated syndrome suggestive of multiple sclerosis

N De Stefano, ML Stromillo, F Rossi, M Battaglini… - PloS one, 2011 - journals.plos.org
Objective To improve the characterization of asymptomatic subjects with brain magnetic
resonance imaging (MRI) abnormalities highly suggestive of multiple sclerosis (MS), a …