Signaling pathways of oxidative stress response: the potential therapeutic targets in gastric cancer

Y Liu, Y Shi, R Han, C Liu, X Qin, P Li, R Gu - Frontiers in immunology, 2023 - frontiersin.org
Gastric cancer is one of the top causes of cancer-related death globally. Although novel
treatment strategies have been developed, attempts to eradicate gastric cancer have been …

Marine-Derived Bisindoles for Potent Selective Cancer Drug Discovery and Development

M Xu, Z Bai, B Xie, R Peng, Z Du, Y Liu, G Zhang… - Molecules, 2024 - mdpi.com
Marine-derived bisindoles exhibit structural diversity and exert anti-cancer influence through
multiple mechanisms. Comprehensive research has shown that the development success …

Allo-targeting of the kinase domain: Insights from in silico studies and comparison with experiments

JY Lee, E Gebauer, MA Seeliger, I Bahar - Current opinion in structural …, 2024 - Elsevier
The eukaryotic protein kinase domain has been a broadly explored target for drug discovery,
despite limitations imposed by its high sequence conservation as a shared modular domain …

神经母细胞瘤动物模型研究进展与应用

谭志刚, 刘锦信, 郑楚雅, 廖文峰, 冯露平, 彭红丽… - 实验动物与比较 …, 2023 - slarc.org.cn
神经母细胞瘤(neuroblastoma, NB) 是儿童最常见的实体恶性肿瘤, 居我国儿童肿瘤发病率第四
位, 占儿童肿瘤死亡人数的15%, 高危患者存活率低. 目前对于NB 的发病及药物治疗机制知之甚 …

Advances and Applications in Animal Models of Neuroblastoma

TAN Zhigang, LIU Jinxin, WL Chuya ZHENG… - Laboratory Animal and …, 2023 - slarc.org.cn
Neuroblastoma (NB) is one of the most common malignant solid tumors in children, ranks
fourth in the incidence of pediatric tumors, and accounts for 15% of pediatric tumor deaths in …